We discuss new physics (NP) contributions to kaon mixing parameter eK, direct CP violation parameter epsilon'/epsilon of K -> pi pi, and rare decays K +-> pi (+) nu nu($) over bar, K-L.-> pi(0) nu nu($) over bar,. and K-L,K- S -> mu(+)mu(-) in the context of general two Higgs doublet model. We focus on contributions of top quark related exotic couplings, and show that simultaneous presence of flavor conserving and flavor violating interactions can lead to large NP effects in kaon sector, while being consistent with the stringent constraints from B physics observables such as Bs(d)- B-s(d)($) over bar mixing, B-s -> mu(+)mu(-), and b. s.. We stress on the importance of correlations between epsilon K, K (+) -> pi(+)nu nu($) over bar. and B-s -> mu(+)mu(-) that can be exploited to distinguish the parameter space corresponding to a light (sub-TeV) or heavy (TeV) scale charged Higgs boson.