Impact of Vitamin D on Osseointegration in Dental Implants: A Systematic Review of Human Studies

被引:2
|
作者
Buzatu, Berivan Laura Rebeca [1 ]
Buzatu, Roxana [2 ]
Luca, Magda Mihaela [3 ]
机构
[1] Victor Babes Univ Med & Pharm Timisoara, Doctoral Sch, Dept Dent Med, Eftimie Murgu Sq 2, Timisoara 300041, Romania
[2] Victor Babes Univ Med & Pharm Timisoara, Fac Dent Med, Dept Dent Aesthet, Eftimie Murgu Sq 2, Timisoara 300041, Romania
[3] Victor Babes Univ Med & Pharm Timisoara, Fac Dent Med, Dept Pediat Dent, Eftimie Murgu Sq 2, Timisoara 300041, Romania
关键词
dental implants; vitamin D; dentistry; SUPPLEMENTATION;
D O I
10.3390/nu16020209
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
This systematic review evaluates the impact of Vitamin D levels on dental implant osseointegration, hypothesizing that optimal Vitamin D enhances success rates, and aims to synthesize data on its relationship with clinical outcomes in implantology. A comprehensive search across PubMed, Cochrane Library, and Web of Science databases included seven peer-reviewed articles meeting the criteria for the review. These studies, conducted between 2008 and 2021, included human subjects and explicitly correlated serum Vitamin D levels with dental implant outcomes, following PRISMA guidelines. The selected studies involved 1462 participants and examined 4450 dental implants. Key findings included a varied implant loss rate ranging from 3.9% to 11.4% across the studies. One study reported a 9.8% implant loss rate, yet found no significant association between Vitamin D receptor polymorphism and implant success. Another study indicated successful implantation following Vitamin D3 supplementation, even in severe deficiency cases. The highest implant loss rate (11.1%) was observed in severely Vitamin D-deficient patients, particularly when compounded by risk factors such as smoking and periodontal disease. Additionally, one study noted significantly improved bone density following post-surgical Vitamin D supplementation for up to 12 weeks. The review supports a link between sufficient Vitamin D levels and successful dental implant osseointegration, suggesting Vitamin D deficiency as a potential risk factor for increased failure and advocating for Vitamin D evaluations in pre-surgical planning to potentially enhance implantology outcomes.
引用
收藏
页数:11
相关论文
共 50 条
  • [31] Analgesics for Dental Implants: A Systematic Review
    Melini, Matteo
    Forni, Andrea
    Cavallin, Francesco
    Parotto, Matteo
    Zanette, Gastone
    [J]. FRONTIERS IN PHARMACOLOGY, 2021, 11
  • [32] Dental Implants Loaded With Bioactive Agents Promote Osseointegration in Osteoporosis: A Review
    Zhang, Cheng
    Zhang, Tianjia
    Geng, Tengyu
    Wang, Xudong
    Lin, Kaili
    Wang, Penglai
    [J]. FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, 2021, 9
  • [33] Osseointegration of Dental Implants in Patients Undergoing Bisphosphonate Treatment: A Literature Review
    Javed, Fawad
    Almas, Khalid
    [J]. JOURNAL OF PERIODONTOLOGY, 2010, 81 (04) : 479 - 484
  • [34] Efficacy of parathyroid hormone supplementation on the osseointegration of implants: a systematic review
    Fawad Javed
    Mohammad D. Al Amri
    Sergio Varela Kellesarian
    Abdulaziz A. Al-Kheraif
    Fahim Vohra
    José Luis Calvo-Guirado
    Hans Malmstrom
    Georgios E. Romanos
    [J]. Clinical Oral Investigations, 2016, 20 : 649 - 658
  • [35] Efficacy of parathyroid hormone supplementation on the osseointegration of implants: a systematic review
    Javed, Fawad
    Al Amri, Mohammad D.
    Kellesarian, Sergio Varela
    Al-Kheraif, Abdulaziz A.
    Vohra, Fahim
    Luis Calvo-Guirado, Jose
    Malmstrom, Hans
    Romanos, Georgios E.
    [J]. CLINICAL ORAL INVESTIGATIONS, 2016, 20 (04) : 649 - 658
  • [36] The Association between Vitamin D and Gut Microbiota: A Systematic Review of Human Studies
    Bellerba, Federica
    Muzio, Valeria
    Gnagnarella, Patrizia
    Facciotti, Federica
    Chiocca, Susanna
    Bossi, Paolo
    Cortinovis, Diego
    Chiaradonna, Ferdinando
    Serrano, Davide
    Raimondi, Sara
    Zerbato, Barbara
    Palorini, Roberta
    Canova, Stefania
    Gaeta, Aurora
    Gandini, Sara
    [J]. NUTRIENTS, 2021, 13 (10)
  • [37] Comparing Short Dental Implants to Standard Dental Implants: Protocol for a Systematic Review
    Rokn, Amir Reza
    Keshtkar, Abbasali
    Monzavi, Abbas
    Hashemi, Kazem
    Bitaraf, Tahereh
    [J]. JMIR RESEARCH PROTOCOLS, 2018, 7 (01):
  • [38] The Impact of Vitamin D Levels on Inflammatory Status: A Systematic Review of Immune Cell Studies
    Calton, Emily K.
    Keane, Kevin N.
    Newsholme, Philip
    Soares, Mario J.
    [J]. PLOS ONE, 2015, 10 (11):
  • [39] Impact of dietary vitamin D on osseointegration in the ovariectomized rat
    Dvorak, Gabriella
    Fuegl, Alexander
    Watzek, Georg
    Tangl, Stefan
    Pokorny, Petra
    Gruber, Reinhard
    [J]. CLINICAL ORAL IMPLANTS RESEARCH, 2012, 23 (11) : 1308 - 1313
  • [40] Clinical efficacy of photobiomodulation on dental implant osseointegration: A systematic review
    Zayed, Sara Mahmoud
    Hakim, Ahmed Adel Abdel
    [J]. SAUDI JOURNAL OF MEDICINE & MEDICAL SCIENCES, 2020, 8 (02) : 80 - 86