Impact of Vitamin D on Osseointegration in Dental Implants: A Systematic Review of Human Studies

被引:2
|
作者
Buzatu, Berivan Laura Rebeca [1 ]
Buzatu, Roxana [2 ]
Luca, Magda Mihaela [3 ]
机构
[1] Victor Babes Univ Med & Pharm Timisoara, Doctoral Sch, Dept Dent Med, Eftimie Murgu Sq 2, Timisoara 300041, Romania
[2] Victor Babes Univ Med & Pharm Timisoara, Fac Dent Med, Dept Dent Aesthet, Eftimie Murgu Sq 2, Timisoara 300041, Romania
[3] Victor Babes Univ Med & Pharm Timisoara, Fac Dent Med, Dept Pediat Dent, Eftimie Murgu Sq 2, Timisoara 300041, Romania
关键词
dental implants; vitamin D; dentistry; SUPPLEMENTATION;
D O I
10.3390/nu16020209
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
This systematic review evaluates the impact of Vitamin D levels on dental implant osseointegration, hypothesizing that optimal Vitamin D enhances success rates, and aims to synthesize data on its relationship with clinical outcomes in implantology. A comprehensive search across PubMed, Cochrane Library, and Web of Science databases included seven peer-reviewed articles meeting the criteria for the review. These studies, conducted between 2008 and 2021, included human subjects and explicitly correlated serum Vitamin D levels with dental implant outcomes, following PRISMA guidelines. The selected studies involved 1462 participants and examined 4450 dental implants. Key findings included a varied implant loss rate ranging from 3.9% to 11.4% across the studies. One study reported a 9.8% implant loss rate, yet found no significant association between Vitamin D receptor polymorphism and implant success. Another study indicated successful implantation following Vitamin D3 supplementation, even in severe deficiency cases. The highest implant loss rate (11.1%) was observed in severely Vitamin D-deficient patients, particularly when compounded by risk factors such as smoking and periodontal disease. Additionally, one study noted significantly improved bone density following post-surgical Vitamin D supplementation for up to 12 weeks. The review supports a link between sufficient Vitamin D levels and successful dental implant osseointegration, suggesting Vitamin D deficiency as a potential risk factor for increased failure and advocating for Vitamin D evaluations in pre-surgical planning to potentially enhance implantology outcomes.
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页数:11
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