Small molecule screen identifies pyrimethamine as an inhibitor of NRF2-driven esophageal hyperplasia

被引：0
|
作者：
Paiboonrungruang, Chorlada
Xiong, Zhaohui
Li, Yahui
Bowman, Brittany
Huang, Zhi
Chen, Vivian
Weissman, Bernard
Williams, Kevin P.
Ben Major, M.
Chen, Xiaoxin
机构：
来源：
CANCER RESEARCH | 2023年 / 83卷 / 07期
关键词：
D O I：
10.1158/1538-7445.AM2023-6237
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
6237
引用
收藏
页数：2
相关论文
共 50 条
  • [41] Small-molecule screen identifies inhibitors of the neuronal K-Cl cotransporter KCC2
    Delpire, Eric
    Days, Emily
    Lewis, L. Michelle
    Mi, Dehui
    Kim, Kwangho
    Lindsley, Craig W.
    Weaver, C. David
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2009, 106 (13) : 5383 - 5388
  • [42] A Small Molecule Screen Identifies Novel Inhibitors of the Neuronal K-Cl cotransporter KCC2
    Delpire, Eric
    Days, Emily
    Mi, Dehui
    Lewis, Michelle
    Lindsley, Craig
    Weaver, David
    FASEB JOURNAL, 2009, 23
  • [43] A high-throughput small molecule screen identifies novel modulators of glycosaminoglycan expression
    Weiss, Ryan J.
    Nora, Chelsea
    Daniele, Elizabeth
    Rother, Sandra
    Gregio, Alessia
    Oukoloff, Killian
    Heynen-Genel, Susanne
    Ballatore, Carlo
    Esko, Jeffrey D.
    GLYCOBIOLOGY, 2020, 30 (12) : 1125 - 1125
  • [44] Small Molecule Kinase Inhibitor Screen Identifies Polo-Like Kinase 1 as a Target for Neuroblastoma Tumor-Initiating Cells
    Grinshtein, Natalie
    Datti, Alessandro
    Fujitani, Mayumi
    Uehling, David
    Prakesch, Michael
    Isaac, Methvin
    Irwin, Meredith S.
    Wrana, Jeffrey L.
    Al-awar, Rima
    Kaplan, David R.
    CANCER RESEARCH, 2011, 71 (04) : 1385 - 1395
  • [45] Drug repurposing screen identifies novel small molecule compounds with potent antifibrotic properties
    Belanger, C.
    Foucart, C.
    Negro, E.
    Dubernet, M.
    Hum, D. W.
    Staels, B.
    Walczak, R.
    JOURNAL OF HEPATOLOGY, 2017, 66 (01) : S605 - S605
  • [46] Dual Myxovirus Screen Identifies a Small-Molecule Agonist of the Host Antiviral Response
    Yan, Dan
    Krumm, Stefanie A.
    Sun, Aiming
    Steinhauer, David A.
    Luo, Ming
    Moore, Martin L.
    Plemper, Richard K.
    JOURNAL OF VIROLOGY, 2013, 87 (20) : 11076 - 11087
  • [47] A high-content small molecule screen identifies novel inducers of definitive endoderm
    Korostylev, Alexander
    Mahaddalkar, Pallavi U.
    Keminer, Oliver
    Hadian, Kamyar
    Schorpp, Kenji
    Gribbon, Philip
    Lickert, Heiko
    MOLECULAR METABOLISM, 2017, 6 (07): : 640 - 650
  • [48] High-Throughput Small Molecule Screen Identifies Modulators of Mitochondrial Function in Neurons
    Varkuti, Boglarka H.
    Liu, Ze
    Kepiro, Miklos
    Pacifico, Rodrigo
    Gai, Yunchao
    Kameneka, Ted
    Davis, Ronald L.
    ISCIENCE, 2020, 23 (03)
  • [49] High-throughput small molecule screen identifies inhibitors of aberrant chromatin accessibility
    Pattenden, Samantha G.
    Simon, Jeremy M.
    Wali, Aminah
    Jayakody, Chatura N.
    Troutman, Jacob
    McFadden, Andrew W.
    Wooten, Joshua
    Wood, Cameron C.
    Frye, Stephen V.
    Janzen, William P.
    Davis, Ian J.
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2016, 113 (11) : 3018 - 3023
  • [50] A whole organism small molecule screen identifies novel regulators of pancreatic endocrine development
    Helker, Christian S. M.
    Mullapudi, Sri-Teja
    Mueller, Laura M.
    Preussner, Jens
    Tunaru, Sorin
    Skog, Oskar
    Kwon, Hyouk-Bum
    Kreuder, Florian
    Lancman, Joseph J.
    Bonnavion, Remy
    Dong, P. Duc Si
    Looso, Mario
    Offermanns, Stefan
    Korsgren, Ole
    Spagnoli, Francesca M.
    Stainier, Didier Y. R.
    DEVELOPMENT, 2019, 146 (14):
12345