A New Briarane Diterpene, Briarlide S from Okinawan Soft Coral Pachyclavularia violacea

被引:0
|
作者
Nagasaka, Misaki [1 ]
Tani, Kazuki [1 ]
Wada, Masahiro [1 ]
Wakatsuki, Miyu [1 ]
Ng, Shean-Yeaw [2 ]
Ishii, Takahiro [1 ]
机构
[1] Univ Ryukyus, Fac Agr, Dept Biosci & Biotechnol, 1 Senbaru, Nishihara, Okinawa 9030213, Japan
[2] Univ Malaysia Sabah, Inst Trop Biol & Conservat, Jalan UMS, Kota Kinabalu 88400, Sabah, Malaysia
关键词
briarane; diterpene; Pachyclavularia violacea; soft coral; BRIAREUM;
D O I
10.1007/s10600-023-04090-9
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
A new briarane diterpene, briarlide S (1), six known compounds, briarlides A, B, E, G, and H (2-6), and brianodin B (7) were isolated from the soft coral, Pachyclavularia violacea, collected from the coast of Apogama, Okinawa prefecture. Chemical structures of the isolated compounds were elucidated by FTIR, NMR, and HR-ESI-MS analyses. The relative stereochemistry of 1 was determined using NOESY. The isolated compounds 1-7 were evaluated for antibacterial activity and brine shrimp toxicity.
引用
收藏
页码:697 / 700
页数:4
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