Advanced Practice Provider Perspectives on Barriers to Managing Seizure Clusters

Patients with treatment-resistant epilepsy may experience seizure clusters. Such medical emergencies require urgent intervention with benzodiazepine rescue medication (RM). Approved RMs for administration in the community include rectal and intranasal routes. The latter provides a more socially acceptable, simple-to-administer option. All nurses, especially nurse practitioners, play a vital role in educating patients and caregivers on when and how to use RMs for seizure emergencies, as well as providing guidance on the se-lection of an appropriate route of administration. This article reviews barriers to effective management of seizure clusters and recommends treatment strategies to overcome them.(c) 2023 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).