RISING: A new framework for model-based few-view CT image reconstruction with deep learning

Medical image reconstruction from low-dose tomographic data is an active research field, recently revolu-tionized by the advent of deep learning. In fact, deep learning typically yields superior results than classical optimization approaches, but unstable results have been reported both numerically and theoretically in the literature. This paper proposes RISING, a new framework for sparse-view tomographic image reconstruction combining an early-stopped Rapid Iterative Solver with a subsequent Iteration Network-based Gaining step. In our two-step approach, the first phase executes very few iterations of a regularized model-based algorithm, whereas the second step completes the missing iterations by means of a convolutional neural network.The proposed method is ground-truth free; it exploits the computational speed and flexibility of a data -driven approach, but it also imposes sparsity constraints to the solution as in the model-based setting. Experiments performed both on a digitally created and on a real abdomen data set confirm the numerical and visual accuracy of the reconstructed RISING images in short computational times. These features make the framework promising to be used on real systems for clinical exams.