Pupillary light reflex is mediated by intrinsic photosensitive retinal ganglion cells (ipRGCs) and the midbrain in human brain. The cells ipRGCs are highly sensitive to blue light (similar to 480 nm). In this study, we evaluated diurnal changes in chromatic sensitivity of ipRGCs by measuring pupillary light reflex. The data showed that sensitivity to red and green light increased from morning to evening, but that to blue decreased from noon to evening. These results indicate that sensitivity of ipRGCs may de-creases in evening.
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Univ Illinois, Dept Ophthalmol & Visual Sci, Chicago, IL USAUniv Illinois, Dept Ophthalmol & Visual Sci, Chicago, IL USA
Park, Jason C.
Moss, Heather E.
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Univ Illinois, Dept Ophthalmol & Visual Sci, Chicago, IL USA
Univ Illinois, Dept Neurol & Rehabil, Chicago, IL USAUniv Illinois, Dept Ophthalmol & Visual Sci, Chicago, IL USA
Moss, Heather E.
McAnany, J. Jason
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Univ Illinois, Dept Ophthalmol & Visual Sci, Chicago, IL USA
Univ Illinois, Dept Psychol, Chicago, IL 60680 USA
Univ Illinois, Dept Bioengn, Chicago, IL USAUniv Illinois, Dept Ophthalmol & Visual Sci, Chicago, IL USA