Generation of two isogenic sickle cell disease induced pluripotent stem cell lines from testicular fibroblasts

被引：0
|
作者：
Harancher, Mitchell R. [1 ,2 ]
Sukhwani, Meena [2 ]
Castro, Carlos A. [2 ]
Hsieh, Michael H. [3 ]
Orwig, Kyle E. [1 ,2 ]
机构：
[1] Univ Pittsburgh, Mol Genet & Dev Biol Grad Program, Sch Med, Pittsburgh, PA 15213 USA
[2] Univ Pittsburgh, Sch Med, Magee Womens Res Inst, Dept Obstet Gynecol & Reprod Sci, Pittsburgh, PA 15213 USA
[3] Childrens Natl Hosp, Washington, DC USA
来源：
STEM CELL RESEARCH | 2023年 / 73卷
关键词：
D O I：
10.1016/j.scr.2023.103257
中图分类号：
Q813 [细胞工程];
学科分类号：
摘要：
Curative bone marrow transplantation (BMT) therapies for sickle cell disease (SCD) can cause infertility. The Fertility Preservation Program (FPP) in Pittsburgh cryopreserves testicular tissues for SCD patients prior to BMT in anticipation that those tissues can be thawed in the future and matured to produce sperm. Here, we generated and validated two isogenic patient-derived induced pluripotent stem cell (iPSC) lines from testicular biopsy fibroblasts of a 12-year-old SCD patient.
引用
下载
收藏
页数：5
相关论文
共 50 条
  • [1] Generation of three isogenic human induced pluripotent stem cell lines from normal neonate skin fibroblasts
    Sandelin, Sanne
    Hakala, Sofia
    Lehtinen, Laura
    Narva, Elisa
    STEM CELL RESEARCH, 2024, 74
  • [2] Generation and characterization of two Vervet monkey induced pluripotent stem cell lines derived from fibroblasts
    Jocher, Jessica
    Edenhofer, Fiona C.
    Mueller, Stefan
    Janssen, Philipp
    Briem, Eva
    Geuder, Johanna
    Enard, Wolfgang
    STEM CELL RESEARCH, 2024, 75
  • [3] Generation of Human Isogenic Induced Pluripotent Stem Cell Lines with CRISPR Prime Editing
    Bonnycastle, Lori L.
    Swift, Amy J.
    Mansell, Erin C.
    Lee, Angela
    Winnicki, Elizabeth
    Li, Elizabeth S.
    Robertson, Catherine C.
    Parsons, Victoria A.
    Huynh, Trung
    Krilow, Chad
    Mohlke, Karen L.
    Erdos, Michael R.
    Narisu, Narisu
    Collins, Francis S.
    CRISPR JOURNAL, 2024, 7 (01): : 53 - 67
  • [4] Induced Pluripotent Stem Cell Lines Derived from Equine Fibroblasts
    Kristina Nagy
    Hoon-Ki Sung
    Puzheng Zhang
    Simon Laflamme
    Patrick Vincent
    Siamak Agha-Mohammadi
    Knut Woltjen
    Claudio Monetti
    Iacovos Prodromos Michael
    Lawrence Charles Smith
    Andras Nagy
    Stem Cell Reviews and Reports, 2011, 7 : 693 - 702
  • [5] Induced Pluripotent Stem Cell Lines Derived from Equine Fibroblasts
    Nagy, Kristina
    Sung, Hoon-Ki
    Zhang, Puzheng
    Laflamme, Simon
    Vincent, Patrick
    Agha-Mohammadi, Siamak
    Woltjen, Knut
    Monetti, Claudio
    Michael, Iacovos Prodromos
    Smith, Lawrence Charles
    Nagy, Andras
    STEM CELL REVIEWS AND REPORTS, 2011, 7 (03) : 693 - 702
  • [6] Generation of two induced pluripotent stem cell lines from patients with Down syndrome
    Zhu, Wenjuan
    Liu, Wenqiang
    Yu, Rebecca
    Manning, Melanie
    Romfh, Anitra Waran
    Wu, Joseph C.
    STEM CELL RESEARCH, 2023, 72
  • [7] Generation of two induced pluripotent stem cell lines from patients with Williams syndrome
    Dai, Yuanyuan
    Zhu, Wenjuan
    Banuelos, Amira G. Flores
    Li, Juana
    Mukherjee, Souhrid
    Algaze, Claudia
    Wu, Joseph C.
    STEM CELL RESEARCH, 2024, 78
  • [8] Generation of induced pluripotent stem cell line from foreskin fibroblasts
    Skrzypczyk, Aniela
    Giri, Shibashish
    Bader, Augustinus
    STEM CELL RESEARCH, 2016, 17 (03) : 572 - 575
  • [9] OPTIMIZATION OF INDUCED PLURIPOTENT STEM CELL GENERATION FROM BOVINE FIBROBLASTS
    Lim, M. L.
    Sumer, H.
    Liu, J.
    Verma, P. J.
    REPRODUCTION FERTILITY AND DEVELOPMENT, 2010, 22 (01) : 350 - 351
  • [10] Generation and characterization of induced pluripotent stem cell lines derived from skin fibroblasts of patients with adrenoleukodystrophy
    Wang, Qiu-Hong
    Liu, Li-Ying
    Wang, Yang-Yang
    He, Wen
    Wang, Jia
    Wang, Jing
    Zou, Li-Ping
    STEM CELL RESEARCH, 2023, 73
12345