Evaluation of Bone Turnover Markers in Patients with Acute and Chronic Leukemia

被引：0
|
作者：
Al-Qaisi, Reem A. [1 ]
Al-Gebori, Abdulnasser M. [1 ]
Alosami, Mohammed Hadi Munshed [2 ]
机构：
[1] Univ Technol Baghdad, Dept Appl Sci, Appl Chemists Div, Baghdad, Iraq
[2] Univ Baghdad, Coll Med, Dept Med, Rheumatol Unit, Baghdad, Iraq
来源：
INDIAN JOURNAL OF CLINICAL BIOCHEMISTRY | 2024年 / 39卷 / 03期
关键词：
Bone remodelling; Imatinib; Osteoclasts; Osteoblasts; PYD; CTX-1; MYELOID-LEUKEMIA; FUNCTIONAL INHIBITION; IMATINIB; CHILDREN; CELLS; INTERLEUKIN-6; RECEPTOR; DISEASE; MARROW;
D O I：
10.1007/s12291-023-01124-5
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
This study investigated different bone biomarkers (cross-linked carboxy-terminal telopeptide of type 1 collagen (CTX-1), pyridinoline (PYD), osteocalcin (OC), interleukin-6 receptor (IL-6R), calcium (Ca), and magnesium (Mg)) in terms of their metabolism in 4 different leukemia subtypes (ALL, AML, CLL and CML). The design was case control study with 30 controls and 60 cases of leukemia patients. Authors have reported many results regarding decrease as well as increase of specific bone biomarker under investigation with each leukemia subtype when compared to control. In addition, Authors reported correlations between each biomarker level and leukemia subtypes.
引用
收藏
页码：392 / 400
页数：9
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