Lung cancer screening: Update, news and perspectives

被引:0
|
作者
Wang, Pascal [1 ]
Chapron, Jeanne [1 ]
Bennani, Souhail [3 ]
Revel, Marie-Pierre [3 ]
Wislez, Marie [1 ,2 ,3 ]
机构
[1] Univ Paris Cite, Hop Cochin, AP HP, Unite Oncol Thorac ,Serv Pneumol, F-75014 Paris, France
[2] Univ Paris, Sorbonne Univ, Ctr Rech Cordeliers, Team Inflammat Complement & Canc,INSERM, F-75006 Paris, France
[3] Univ Paris Cite, Hop Cochin, AP HP, Serv Radiol, F-75014 Paris, France
关键词
Screening; Lung cancer; CT scan; Lung nodule; Solitary pulmonary nodule; Tobacco smoking; DOSE CT; COMPUTED-TOMOGRAPHY; SPIRAL CT; TRIAL; MORTALITY; FEASIBILITY; ASSOCIATION; MULTICENTER; SURVIVAL; FRANCE;
D O I
10.1016/j.bulcan.2022.11.006
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Lung cancer is the leading cause of cancer death in France and worldwide (20 % of cancer deaths). This mortality is partly linked to an overrepresentation of metastatic stages at diagnosis (approximately 55 % of lung cancers at diagnosis). Low-dose chest CT in a target population to detect early forms accessible to radical treatment has been evaluated through multiple rando-mized trials (NLST, NELSON, MILD, DANTE. . .). These trials demonstrated a reduction in lung cancer specific mortality. The current problem is to integrate a CT screening policy CT at a national level, which should be both efficient and cost-effective, while presenting the least harms for the eligible population. Finally, it is necessary to optimize the participation of the eligible population and particularly in the most deprived areas and ensure the proper implementation of smoking cessation measures.
引用
收藏
页码:42 / 54
页数:13
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