CHIP-JAK2V617F, chronic inflammation, abnormal megakaryocyte morphology, organ failure, and multimorbidties

被引:5
|
作者
Hasselbalch, Hans Carl [1 ,2 ,6 ]
Kristiansen, Marie Hvelplund [1 ,3 ]
Kjaer, Lasse [2 ]
Skov, Vibe [2 ]
Larsen, Morten Kranker [1 ,2 ]
Ellervik, Christina [1 ,4 ,5 ]
Wienecke, Troels [1 ,3 ]
机构
[1] Univ Copenhagen, Fac Hlth & Med Sci, Dept Clin Med, Copenhagen, Denmark
[2] Zealand Univ Hosp, Dept Hematol, Roskilde, Denmark
[3] Zealand Univ Hosp, Dept Neurol, Roskilde, Denmark
[4] Dept Data & Data Support, Reg Zealand, Soro, Denmark
[5] Harvard Med Sch, Childrens Hosp Boston, Dept Lab Med, Boston, MA USA
[6] Zealand Univ Hosp, Dept Hematol, Vestermarksvej 5-7, DK-4000 Roskilde, Denmark
关键词
ISCHEMIC-STROKE; JAK2V617F;
D O I
10.1182/bloodadvances.2023012190
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:681 / 682
页数:2
相关论文
共 50 条
  • [21] Prevalence of the JAK2-V617F mutation in Taiwanese patients with chronic myeloproliferative disorders
    Lieu, C. -H.
    Wu, H. -S.
    Hon, Y. -C.
    Tsai, W. -H.
    Yang, C. -F.
    Wang, C. -C.
    Lin, Y. -C.
    Shih, C. -H.
    Hsu, H. -C.
    INTERNAL MEDICINE JOURNAL, 2008, 38 (6A) : 422 - 426
  • [22] Widespread occurrence of the JAK2 V617F mutation in chronic myeloproliferative disorders
    Jones, AV
    Kreil, S
    Zoi, K
    Waghorn, K
    Curtis, C
    Zhang, LY
    Score, J
    Seear, R
    Chase, AJ
    Grand, FH
    White, H
    Zoi, C
    Loukopoulos, D
    Terpos, E
    Vervessou, EC
    Schultheis, B
    Emig, M
    Ernst, T
    Lengfelder, E
    Hehlmann, R
    Hochhaus, A
    Oscier, D
    Silver, RT
    Reiter, A
    Cross, NCP
    BLOOD, 2005, 106 (06) : 2162 - 2168
  • [23] Sex differences in the JAK2V617F allele burden in chronic myeloproliferative disorders
    Stein, Brady L.
    Williams, Donna M.
    Wang, Nae-Yuh
    Rogers, Ophelia
    Isaacs, Mary Ann
    Pemmaraju, Naveen
    Spivak, Jerry L.
    Moliterno, Alison R.
    HAEMATOLOGICA-THE HEMATOLOGY JOURNAL, 2010, 95 (07): : 1090 - 1097
  • [24] JAK2V617F Hematopoietic Stem Cells Exhibit a Blunted Response to Acute Inflammation
    Craver, Brianna
    Lai, Hew Yeng
    Morse, Sarah
    Brooks, Stefan
    Kim, Daniel
    Fleischman, Angela G.
    BLOOD, 2017, 130
  • [25] IL-10R Inhibition Selects for Jak2V617F Hematopoiesis By Augmenting Inflammation Induced Exhaustion of Wild-Type but Not Jak2V617F Hematopoietic Stem Cells
    Fleischman, Angela
    Lai, Hew Yeng
    Mehrota-Venkat, Nitya
    Trieu, Tiffany
    Han, Tiffany
    Ramanathan, Gajalakshmi
    Hoover, Brianna
    BLOOD, 2021, 138
  • [26] A New Murine Model of Clonal Hematopoiesis Investigates JAK2V617F in Heart Failure
    Patel, Aniruddh P.
    Natarajan, Pradeep
    JACC-BASIC TO TRANSLATIONAL SCIENCE, 2019, 4 (06): : 698 - 700
  • [27] TNFR1 Blockade Rather then TNFR2 Blockade Reduces Chronic Inflammation in JAK2+/V617F Mice
    Mueller, Peter
    Edelmann-Stephan, Baerbel
    Richter, Fabian
    Pfizenmaier, Klaus
    Fischer, Thomas
    BLOOD, 2019, 134
  • [28] Incidence and significance of the JAK2 V617F mutation in patients with chronic myeloproliferative disorders
    Langabeer, S. E.
    Ainle, F. Ni
    Conneally, E.
    Lawler, M.
    IRISH JOURNAL OF MEDICAL SCIENCE, 2007, 176 (02) : 105 - 109
  • [29] JAK2 V617F mutation detection in chronic myeloproliferative neoplasms by digital PCR
    Waterhouse, M.
    Pfeifer, D.
    Follo, M.
    Bertz, H.
    Finke, J.
    ONCOLOGY RESEARCH AND TREATMENT, 2017, 40 : 196 - 196
  • [30] Incidence and significance of the JAK2 V617F mutation in patients with chronic myeloproliferative disorders
    S. E. Langabeer
    F. Ni Ainle
    E. Conneally
    M. Lawler
    Irish Journal of Medical Science, 2007, 176 : 105 - 109