Low-grade dysplasia in Barrett's esophagus: A problematic diagnosis

被引：0

作者：

Sarem, Muhannad ^{[1
,2
]}

Cerezo, Francisco J. Martinez ^{[1
,3
]}

Favieres, Maria Lujan Salvia ^{[4
]}

Corti, Rodolfo ^{[5
,6
]}

机构：

[1] Hosp Univ St Joan Reus, Serv Aparell Digestiu, Tarragona, Spain

[2] Inst Univ Ciencias Salud, Escuela Med, Fdn Hector A, Dept Ciencias Morfol, Buenos Aires, Argentina

[3] Univ Rovira & Virgili, Fundacio Inst Invest Sanit Pere Virgili, Dept Med & Cirurgia, Tarragona, Spain

[4] Hosp Dr Diego Thompson, Dept Cirugia, San Martin, Buenos Aires, Argentina

[5] Hosp Gastroenterol Bonorino Udaondo, Unidad Esofago & Estomago, Buenos Aires, Argentina

[6] Univ Buenos Aires, Escuela Med, Unidad Acad, Buenos Aires, Argentina

来源：

GASTROENTEROLOGIA Y HEPATOLOGIA | 2023年 / 46卷 / 08期

关键词：

Barrett's esophagus; Low-grade dysplasia; Progression risk; MALIGNANT PROGRESSION; INCREASED RISK; ADENOCARCINOMA; MANAGEMENT; DISEASE; EPIDEMIOLOGY; SURVEILLANCE; GUIDELINES; SOCIETY; CANCER;

D O I：

10.1016/j.gastrohep.2022.10.002

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Although low-grade dysplasia (LGD) in Barrett's esophagus (BE) is a histopathological diagnosis based on different histological abnormalities, it is still problematic for different reasons. Patients without confirmed diagnosis of LGD undergo unnecessary and intensified follow-up where the risk of progression is low in the majority of cases. In contrast, the presence of confirmed LGD indicates a high risk of progression. In this article we try to address these reasons focusing on re-confirmation of LGD diagnosis, interobserver agreement, and persistent confirmed LGD. The progression risk of LGD to high-grade dysplasia and esophageal adenocarcinoma will also be reviewed. (c) 2022 Elsevier Espana, S.L.U. All rights reserved.

引用

页码：637 / 644

页数：8

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