Understanding how IL-2 cytokine synergizes with PD-1 therapy during chronic viral infection

被引：0
|
作者：
Hashimoto, Masao
机构：
来源：
CANCER RESEARCH | 2023年 / 83卷 / 08期
关键词：
D O I：
10.1158/1538-7445.AM2023-LB100
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
LB100
引用
收藏
页数：2
相关论文
共 50 条
  • [41] PRaG regimens (PD-1 inhibitor combined with radiotherapy and GM-CSF with or not IL-2) rechallenge for patients with acquiring resistance to PD-1/PD-L1 inhibitors in refractory advanced solid tumors
    Xu, Meiling
    Xing, Pengfei
    Kong, Yuehong
    Zhang, Chenyang
    Zhao, Xiangrong
    Zhang, Junjun
    Zhang, Liyuan
    JOURNAL OF CLINICAL ONCOLOGY, 2022, 40 (16)
  • [42] Alveolar macrophage dysfunction and increased PD-1 expression during chronic SIV infection of rhesus macaques
    Hunegnaw, Ruth
    Mushtaq, Zuena
    Enyindah-Asonye, Gospel
    Hoang, Tanya
    Robert-Guroff, Marjorie
    JOURNAL OF IMMUNOLOGY, 2019, 202 (01):
  • [43] Alveolar Macrophage Dysfunction and Increased PD-1 Expression During Chronic SIV Infection of Rhesus Macaques
    Hunegnaw, Ruth
    Mushtaq, Zuena
    Enyindah-Asonye, Gospel
    Hoang, Tanya
    Robert-Guroff, Marjorie
    FRONTIERS IN IMMUNOLOGY, 2019, 10
  • [44] PD-1 Inhibitor Combined with Hypofractionated Radiotherapy and GM-CSF with or without IL-2 (PRaG Regimens) Rechallenge for Acquiring Resistance to PD-1/ PD-L1 Inhibitor in Advanced Solid Tumors
    Xu, M.
    Xing, P.
    Kong, Y.
    Zhang, C.
    Zhao, X.
    Zhang, J.
    Zhang, L.
    INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2022, 114 (03): : E427 - E428
  • [45] Mathematical model of tumor immune microenvironment with application to the combined therapy targeting the PD-1/PD-L1 pathway and IL-10 cytokine antibody
    Zixin Zhang
    Xiyin Liang
    Jianyong Qin
    Jinzhi Lei
    Theory in Biosciences, 2025, 144 (1) : 19 - 43
  • [46] Enhanced Expression of PD-1 Modulates CD4+Foxp3+Regulatory T Cell Homeostasis during Low-Dose IL-2 Therapy in Patients with Chronic Graft-Versus-Host Disease
    Asano, Takeru
    Kim, Haesook T.
    Koreth, John
    Soiffer, Robert J.
    Meguri, Yusuke
    Yoshioka, Takanori
    Yagita, Hideo
    Tanimoto, Mitsune
    Ritz, Jerome
    Matsuoka, Ken-ichi
    BLOOD, 2014, 124 (21)
  • [47] Low-dose IL-2 therapy compensates for metabolic shifts and reverses anxiety-like behavior in PD-1 deficiency-induced autoimmunity
    Cui Lv
    Hao Zhang
    Zifa Li
    Hao Zhang
    Yu Zhang
    Ronghui Li
    Sheng Wei
    Di Yu
    Cellular & Molecular Immunology, 2021, 18 : 1336 - 1338
  • [48] IFN-α, IFN-γ, IL-2 combined with TNF-α for predicting efficacy of PD-1 inhibitors combination therapy in patients with solid cancers.
    Xing, Penghui
    Zhang, Jinyan
    Liu, Rongfeng
    Wang, Junyan
    Ma, Ming
    Wang, Lixing
    Jiao, Wenjing
    Shao, Junguo
    Wang, Yuxiang
    He, Hongtao
    Shan, Baoen
    Shi, Jian
    JOURNAL OF CLINICAL ONCOLOGY, 2021, 39 (15)
  • [49] Low-dose IL-2 therapy compensates for metabolic shifts and reverses anxiety-like behavior in PD-1 deficiency-induced autoimmunity
    Lv, Cui
    Zhang, Hao
    Li, Zifa
    Zhang, Hao
    Zhang, Yu
    Li, Ronghui
    Wei, Sheng
    Yu, Di
    CELLULAR & MOLECULAR IMMUNOLOGY, 2021, 18 (05) : 1336 - 1338
  • [50] PD-1 Signaling Promotes Control of Chronic Viral Infection by Restricting Type-I-Interferon-Mediated Tissue Damage
    Raju, Saravanan
    Verbaro, Daniel J.
    Egawa, Takeshi
    CELL REPORTS, 2019, 29 (09): : 2556 - +
12345