collider bias;
inverse probability weighting;
linear models;
directed acyclic graph;
post-outcome collider bias;
SELECTION BIAS;
CAUSAL;
D O I:
10.1177/00491241211043131
中图分类号:
O1 [数学];
C [社会科学总论];
学科分类号:
03 ;
0303 ;
0701 ;
070101 ;
摘要:
We consider the problem of bias arising from conditioning on a post-outcome collider. We illustrate this with reference to Elwert and Winship (2014) but we go beyond their study to investigate the extent to which inverse probability weighting might offer solutions. We use linear models to derive expressions for the bias arising in different kinds of post-outcome confounding, and we show the specific situations in which inverse probability weighting will allow us to obtain estimates that are consistent or, if not consistent, less biased than those obtained via ordinary least squares regression.
机构:
Bristol Myers Squibb, Ctr Observat Res & Data Sci, Uxbridge, Middx, EnglandBristol Myers Squibb, Ctr Observat Res & Data Sci, Uxbridge, Middx, England
Allan, Victoria
Ramagopalan, Sreeram, V
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机构:
Bristol Myers Squibb, Ctr Observat Res & Data Sci, Uxbridge, Middx, EnglandBristol Myers Squibb, Ctr Observat Res & Data Sci, Uxbridge, Middx, England
Ramagopalan, Sreeram, V
Mardekian, Jack
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机构:
Pfizer Inc, Stat Global Biometr & Data Management, New York, NY USABristol Myers Squibb, Ctr Observat Res & Data Sci, Uxbridge, Middx, England
Mardekian, Jack
Jenkins, Aaron
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机构:
Pfizer Ltd, Patient Hlth & Impact, Outcomes & Evidence, Tadworth, EnglandBristol Myers Squibb, Ctr Observat Res & Data Sci, Uxbridge, Middx, England
Jenkins, Aaron
Li, Xiaoyan
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机构:
Bristol Myers Squibb, Worldwide Hlth Econ & Outcomes Res, Lawrenceville, NJ USABristol Myers Squibb, Ctr Observat Res & Data Sci, Uxbridge, Middx, England
Li, Xiaoyan
Pan, Xianying
论文数: 0引用数: 0
h-index: 0
机构:
Bristol Myers Squibb, Pharmacoepidemiol, Lawrenceville, NJ USABristol Myers Squibb, Ctr Observat Res & Data Sci, Uxbridge, Middx, England
Pan, Xianying
Luo, Xuemei
论文数: 0引用数: 0
h-index: 0
机构:
Pfizer Inc, Patient Hlth & Impact, Outcomes & Evidence, Groton, CT 06340 USABristol Myers Squibb, Ctr Observat Res & Data Sci, Uxbridge, Middx, England
机构:
Imperial Coll London, Imperial Clin Trials Unit, Stadium House,68 Wood Lane, London W12 7RH, EnglandImperial Coll London, Imperial Clin Trials Unit, Stadium House,68 Wood Lane, London W12 7RH, England
Raad, Hanaya
Cornelius, Victoria
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Imperial Coll London, Imperial Clin Trials Unit, Stadium House,68 Wood Lane, London W12 7RH, EnglandImperial Coll London, Imperial Clin Trials Unit, Stadium House,68 Wood Lane, London W12 7RH, England
Cornelius, Victoria
Chan, Susan
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机构:
Guys & St Thomas NHS Fdn Trust, Childrens Allergy, London SE1 7EH, England
Kings Coll London, Sch Life Course Sci, London, England
Kings Hlth Partners, Sch Immunol & Microbial Sci, London, EnglandImperial Coll London, Imperial Clin Trials Unit, Stadium House,68 Wood Lane, London W12 7RH, England
Chan, Susan
Williamson, Elizabeth
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机构:
London Sch Hyg & Trop Med, Fac Epidemiol & Populat Hlth, Dept Med Stat, London WC1E 7HT, EnglandImperial Coll London, Imperial Clin Trials Unit, Stadium House,68 Wood Lane, London W12 7RH, England
Williamson, Elizabeth
Cro, Suzie
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Imperial Coll London, Imperial Clin Trials Unit, Stadium House,68 Wood Lane, London W12 7RH, EnglandImperial Coll London, Imperial Clin Trials Unit, Stadium House,68 Wood Lane, London W12 7RH, England
机构:
ICES, Toronto, ON, Canada
Univ Toronto, Inst Hlth Policy Management & Evaluat, Toronto, ON, Canada
Sunnybrook Res Inst, Schulich Heart Res Program, Toronto, ON, CanadaICES, Toronto, ON, Canada
Austin, Peter C.
Fine, Jason P.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Pittsburgh, Dept Stat, Pittsburgh, PA USAICES, Toronto, ON, Canada
机构:
Victoria Univ, Inst Sport Exercise & Act Living, POB 14428, Melbourne, Vic 8001, AustraliaVictoria Univ, Inst Sport Exercise & Act Living, POB 14428, Melbourne, Vic 8001, Australia
Kovalchik, Stephanie A.
Martino, Steven C.
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h-index: 0
机构:
RAND Corp, 4570 Fifth Ave, Pittsburgh, PA 15213 USAVictoria Univ, Inst Sport Exercise & Act Living, POB 14428, Melbourne, Vic 8001, Australia
Martino, Steven C.
Collins, Rebecca L.
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h-index: 0
机构:
RAND Corp, 1776 Main St, Santa Monica, CA 90401 USAVictoria Univ, Inst Sport Exercise & Act Living, POB 14428, Melbourne, Vic 8001, Australia
Collins, Rebecca L.
Shadel, William G.
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h-index: 0
机构:
RAND Corp, 4570 Fifth Ave, Pittsburgh, PA 15213 USAVictoria Univ, Inst Sport Exercise & Act Living, POB 14428, Melbourne, Vic 8001, Australia
Shadel, William G.
D'Amico, Elizabeth J.
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h-index: 0
机构:
RAND Corp, 1776 Main St, Santa Monica, CA 90401 USAVictoria Univ, Inst Sport Exercise & Act Living, POB 14428, Melbourne, Vic 8001, Australia
D'Amico, Elizabeth J.
Becker, Kirsten
论文数: 0引用数: 0
h-index: 0
机构:
RAND Corp, 1776 Main St, Santa Monica, CA 90401 USAVictoria Univ, Inst Sport Exercise & Act Living, POB 14428, Melbourne, Vic 8001, Australia