Effects of palliative intrathecal analgesia on patients with refractory cancer bone pain

被引：0

作者：

Haraga, Isao ^{[1
,2
]}

Kosugi, Toshifumi ^{[3
]}

Sadashima, Eiji ^{[4
]}

Yumiba, Tomoko ^{[3
]}

Kubo, Mayuko ^{[3
]}

Ishikawa-Konishi, Asako ^{[3
,5
]}

Akiyoshi, Kozaburo ^{[1
]}

机构：

[1] Fukuoka Univ, Fac Med, Dept Anesthesiol, 7-45-1 Nanakuma,Jonan Ku, Fukuoka, Fukuoka 8140180, Japan

[2] Kitakyushu Municipal Med Ctr, Dept Anesthesiol, 2-1-1 Bashaku,Kokurakita Ku, Kitakyushu, Fukuoka 8028561, Japan

[3] Saga Ken Med Ctr Koseikan, Dept Palliat Care, 400 Nakabaru, Saga, Saga 8408571, Japan

[4] Saga Ken Med Ctr Koseikan, Med Res Inst, 400Nakabaru, Saga, Saga 8408571, Japan

[5] Tachikawa Home Care Clin, 5-71-16 Saiwai Cho, Tachikawa, Tokyo 1900002, Japan

来源：

JOURNAL OF ANESTHESIA | 2024年 / 38卷 / 03期

关键词：

Palliative care; Cancer pain; Bone Metastasis; Spinal injections; RANDOMIZED CLINICAL-TRIAL; COMPREHENSIVE MEDICAL-MANAGEMENT; UNRESECTABLE PANCREATIC-CANCER; DRUG-RELATED TOXICITY; LONG-TERM; CELIAC PLEXUS; SURVIVAL; SYSTEM; IMPACT; BUPIVACAINE;

D O I：

10.1007/s00540-024-03338-0

中图分类号：

R614 [麻醉学];

学科分类号：

100217 ;

摘要：

This study examined the effects of intrathecal analgesia (ITA) using an extracorporeal pump with a subcutaneous port system in cancer patients with bone metastasis. Among the patients who died of cancer with bone metastasis at the palliative care unit of our institution, 11 who received ITA were selected. Changes in pain, opioid doses, the palliative prognostic index (PPI), and Eastern Cooperative Oncology Group Performance Scale-after ITA were assessed. Pain, opioid doses, and PPI decreased after ITA (P = 0.002, 0.002, and 0.017). ITA for cancer patients with increased PPI due to refractory cancer bone pain decreased pain, opioid doses, and PPI.

引用

页码：405 / 411

页数：7

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