Rheumatic Heart Disease in the Developing World

被引:8
|
作者
Simpson, Michael T. [1 ]
Kachel, Mateusz [1 ]
Neely, Robert C. [2 ]
Erwin, W. Clinton [1 ]
Yasin, Aleena [3 ]
Patel, Amisha [4 ]
Rao, Dasari Prasada [5 ]
Pandey, Kaushal [6 ]
George, Isaac [1 ,7 ]
机构
[1] Columbia Univ, Coll Phys & Surg, Dept Surg, Div Cardiac Thorac & Vasc Surg, New York, NY USA
[2] Cardiothorac & Vasc Surg, Austin, TX USA
[3] Stanford Univ, Dept Cardiothorac Surg, Palo Alto, CA USA
[4] Mt Sinai Med Ctr, Div Cardiol, New York, NY USA
[5] Apollo Spectra Hosp, Dept Cardiothorac Surg, Hyderabad, India
[6] Hinduja Hosp, Ctr Cardiac Care, Mumbai, India
[7] New York Presbyterian Hosp, Struct Heart Dis, Milstein Hosp Bldg,177 Ft Washington Ave,7th Floor, New York, NY 10032 USA
来源
关键词
Mitral valve repair; Mitral valve replacement; Rheumatic heart disease; BENZATHINE PENICILLIN-G; STREPTOCOCCAL PHARYNGITIS; MITRAL COMMISSUROTOMY; PERCUTANEOUS BALLOON; COST-EFFECTIVENESS; FOLLOW-UP; CARDIAC-SURGERY; FEVER; PREVENTION; CHILDREN;
D O I
10.1016/j.shj.2023.100219
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Despite recent public policy initiatives, rheumatic heart disease (RHD) remains a major source of morbidity worldwide. Rheumatic heart disease occurs as a sequela of Streptococcus pyogenes (group A streptococcal [GAS]) infection in patients with genetic susceptibility. Strategies for prevention of RHD or progression of RHD include prevention of GAS infection with community initiatives, effective treatment of GAS infection, and secondary prophylaxis with intramuscular penicillin. The cardiac surgical community has attempted to improve the availability of surgery in RHD-endemic areas with some success, and operative techniques and outcomes of valve repair continue to improve, potentially offering patients a safer, more durable operation. Innovation offers hope for a more scalable solution with improved biomaterials and transcatheter delivery technology; however, cost remains a barrier.
引用
收藏
页数:9
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