Mapping the binding site of NS309, a superagonistic positive gating modulator for the calcium-activated potassium channel KCa3.1

被引：0
|
作者：
Nasburg, Joshua A. [1 ]
机构：
[1] Univ Calif Davis, Sch Med, Dept Pharmacol, Davis, CA USA
来源：
BIOPHYSICAL JOURNAL | 2023年 / 122卷 / 03期
关键词：
D O I：
暂无
中图分类号：
Q6 [生物物理学];
学科分类号：
071011 ;
摘要：
1223-Pos
引用
收藏
页码：252A / 252A
页数：1
相关论文
共 47 条
  • [21] Involvement of the calcium-activated potassium channel (KCA3.1) in apoptotic neurodegeneration and neuroinflammation induced by ethanol in neonatal mice
    Saito, M.
    Subbanna, S.
    Zhang, X.
    Nandwana, N. K.
    Smiley, J. F.
    Wilson, D. A.
    Das, B. C.
    ALCOHOL-CLINICAL AND EXPERIMENTAL RESEARCH, 2023, 47 : 179 - 179
  • [22] Neuronal expression of the intermediate conductance calcium-activated potassium channel KCa3.1 in the mammalian central nervous system
    Turner, Ray W.
    Kruskic, Mirna
    Teves, Michelle
    Scheidl-Yee, Teresa
    Hameed, Shahid
    Zamponi, Gerald W.
    PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY, 2015, 467 (02): : 311 - 328
  • [23] Intermediate-conductance calcium-activated potassium channel, KCa3.1, plays an important role in macrophage migration in atherosclerosis
    Miura, Hiroto
    Toyama, Kazuyoshi
    Fujiwara, Yoshimasa
    Saito, Takashi
    Hatoum, Ossama
    Gutterman, David
    ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2007, 27 (06) : E71 - E71
  • [24] Intermediate conductance calcium-activated potassium channel, KCa3.1, plays an important role in macrophage (MO) migration in atheroscierosis
    Toyama, Kazuyoshi
    Saito, Takashi
    Fujiwara, Yoshimasa
    Hatoum, Ossama A.
    Gutterman, David D.
    Miura, Hiroto
    FASEB JOURNAL, 2007, 21 (06): : A854 - A854
  • [25] Role of the calcium-activated K+ channel KCa3.1 in the progression of pancreatic ductal adenocarcinoma
    Soret, B.
    Petho, Z.
    Lehen'kyi, V.
    Schwab, A.
    ACTA PHYSIOLOGICA, 2022, 236 : 687 - 689
  • [26] Activation of endothelial and epithelial KCa2.3 calcium-activated potassium channels by NS309 relaxes human small pulmonary arteries and bronchioles
    Kroigaard, Christel
    Dalsgaard, Thomas
    Nielsen, Gorm
    Laursen, Britt E.
    Pilegaard, Hans
    Kohler, Ralf
    Simonsen, Ulf
    BRITISH JOURNAL OF PHARMACOLOGY, 2012, 167 (01) : 37 - 47
  • [27] Augmenting the activity of calcium-activated potassium channel KCa3.1 revitalizes T-cell function in the immunosuppressive tumor microenvironment
    Verma, Navin K.
    Wong, Brandon Han Siang
    Ong, Seow Theng
    Goay, Stephanie Shee Min
    Ho, Ying Swan
    Chen, Shuwen
    Bi, Xuezhi
    Shim, Heesung
    Wulff, Heike
    Webster, Richard D.
    Shelat, Vishalkumar G.
    Chandy, K. George
    BIOPHYSICAL JOURNAL, 2023, 122 (03) : 256A - 256A
  • [28] The intermediate-conductance calcium-activated potassium channel KCa3.1 contributes to alkalinization-induced vascular calcification in vitro
    Bai, Yaling
    Xu, Jinsheng
    Yang, Shuo
    Zhang, Huiran
    He, Lei
    Zhou, Wei
    Cheng, Meijuan
    Zhang, Shenglei
    JOURNAL OF CLINICAL LABORATORY ANALYSIS, 2021, 35 (08)
  • [29] New Positive Ca2+-Activated K+ Channel Gating Modulators with Selectivity for KCa3.1
    Coleman, Nichole
    Brown, Brandon M.
    Olivan-Viguera, Aida
    Singh, Vikrant
    Olmstead, Marilyn M.
    Valero, Marta Sofia
    Kohler, Ralf
    Wulff, Heike
    MOLECULAR PHARMACOLOGY, 2014, 86 (03) : 342 - 357
  • [30] The role of nitric oxide (NO) in the expression of the human intermediate and small conductance calcium-activated potassium channels, KCa3.1 and KCa2.3
    Jones, Heather Marie
    Hussain, Yusaf M.
    FASEB JOURNAL, 2016, 30
12345