NUCLEAR MORPHOMETRY AND ITS PROGNOSTIC SIGNIFICANCE IN LARYNGEAL SQUAMOUS CELL CARCINOMAS

被引：0
|
作者：
郑虹
林代诚
洪邦泰
姚先莹
机构：
来源：
中华医学杂志(英文版) | 1992年 / 05期
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中图分类号：
R [医药、卫生];
学科分类号：
10 ;
摘要：
The five parameters including nuclear area（NA）,nuclear perimeter（NP）,nuclear diameter（ND）,axisratio and nuclear roundness were evaluated withMIAS200 Image Analysis System（SichuanUniversity,Chengdu）in 45 patients with laryngealprimary squamous cell carcinoma,which were con-firmed pathologically and operated on from January1977 to October 1987.The results showed that NA,NP and ND are important prognostic indicators.Thesurvival rate in patients with large nuclei（NA≥73μm,NP≥32.5μm,ND≥12μm）was significantly lowerthan that in those with small nuclei（NA<73μm,NP<32.5μm,ND<12μm）(P<0.0025).These find-ings strongly suggest that patients with laryngealsquamous cell carcinoma with large nuclei should betreated more aggressively.
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页码：410 / 414
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