Effect of types of solid lipids on the physicochemical properties and self-aggregation of amphotericin B loaded nanostructured lipid carriers(NLCs)

被引:0
|
作者
Pataranapa Nimtrakul
Waree Tiyaboonchai
Supaporn Lamlertthon
机构
[1] Faculty of Pharmaceutical Sciences
[2] Faculty of Medical Sciences
[3] Naresuan University
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D O I
暂无
中图分类号
R943 [制剂学];
学科分类号
100602 ; 100702 ;
摘要
Amphotericin B (Am B), a polyene antibiotic, is one of the gold standards for the treatment of systemic fungal infections and leishmaniasis. Nowadays, only intravenous administration of Am B has been available; because Am B is poorly absorbed from the gastrointestinal (GI) tract due to its low aqueous solubility. Currently, 2 forms of Am B are available. The first is a mixture
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页码:172 / 173
页数:2
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