IS4 peptide forms ion channel in rat skeletal muscle cell membrane

被引：0
|
作者：
BAO Lin
College of Life Sciences
State Key Laboratory for Structural Chemistry of Unstable and Stable Species
机构：
来源：
Science Bulletin | 1999年 / 24期
关键词：
synthetic IS4 peptide; cation selective channel; rat skeletal myotube;
D O I：
暂无
中图分类号：
Q952 [动物细胞学];
学科分类号：
071009 ;
摘要：
A 22-mer peptide, identical to the primary sequence of domain I segment 4 (IS4) of rat brain sodium channel I, has been synthesized. IS4 peptide can incorporate into cultured rat skeletal myotube membranes and form ion channels. With patch clamp cell-attached technique single channel currents through IS4 channels can be recorded. The single channel conduc-
引用
收藏
页码：2232 / 2236
页数：5
相关论文
共 50 条
  • [1] IS4 peptide forms ion channel in rat skeletal muscle cell membrane
    Bao, L
    Miao, ZW
    Zhou, PA
    Jiang, Y
    Zhang, RJ
    Tang, YQ
    [J]. CHINESE SCIENCE BULLETIN, 1999, 44 (24): : 2232 - 2236
  • [2] Conformational studies of rat brain sodium ion channel segment IS4 in different media
    Miao, ZW
    Jiang, Y
    Aimoto, S
    Xu, XJ
    Tang, YQ
    [J]. PEPTIDES: FRONTIERS OF PEPTIDES SCIENCE, 1999, : 491 - 492
  • [3] IS3 peptide-formed ion channels in rat skeletal muscle cell membranes
    Bao, L
    Miao, ZW
    Zhou, PA
    Jiang, Y
    Sha, YL
    Zhang, RJ
    Tang, YC
    [J]. FEBS LETTERS, 1999, 446 (2-3) : 351 - 354
  • [4] ION-CHANNEL ACTIVITY IN LOBSTER SKELETAL-MUSCLE MEMBRANE
    WORDEN, MK
    RAHAMIMOFF, R
    KRAVITZ, EA
    [J]. JOURNAL OF EXPERIMENTAL BIOLOGY, 1993, 182 : 113 - 130
  • [5] Ion channel mutations and diseases of skeletal muscle
    Barchi, RL
    [J]. NEUROBIOLOGY OF DISEASE, 1997, 4 (3-4) : 254 - 264
  • [6] Effects of channel - forming antibiotics on ion transport in muscle cell membrane
    Schvinka, N
    [J]. PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY, 1996, 65 : PC102 - PC102
  • [7] Expression of water channel MIWC/AQP4 in rat skeletal muscle
    Frigeri, A
    Nicchia, GP
    Valenti, G
    Svelto, M
    [J]. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY, 1997, 434 (02): : 123 - 123
  • [8] Sodium channel regulation of skeletal muscle membrane excitability
    Ruff, RL
    [J]. FRONTIERS OF NEUROLOGY: A SYMPOSIUM IN HONOR OF FRED PLUM, 1997, 835 : 64 - 76
  • [9] CHARACTERIZATION OF ION CHANNELS ON THE SURFACE-MEMBRANE OF ADULT-RAT SKELETAL-MUSCLE
    CHUA, M
    BETZ, WJ
    [J]. BIOPHYSICAL JOURNAL, 1991, 59 (06) : 1251 - 1260
  • [10] DEVELOPMENTAL CHANGES OF MEMBRANE ELECTRICAL PROPERTIES IN A RAT SKELETAL-MUSCLE CELL LINE
    KIDOKORO, Y
    [J]. JOURNAL OF PHYSIOLOGY-LONDON, 1975, 244 (01): : 129 - 143
12345