Preventive role of palladium-103 radioactive stent on in-stent restenosis in rabbit iliac arteries

被引：0
|
作者：
LUO Quan-Yong
机构：
来源：
Nuclear Science and Techniques | 2005年 / 01期
关键词：
Restenosis; Palladium-103; Radiation; Stent; Radioisotopes;
D O I：
暂无
中图分类号：
R654.2 [心脏];
学科分类号：
1002 ; 100210 ;
摘要：
The abilility of γ-emitting palladium-103 stent implantation to inhibit in-stent restenosis in rabbit iliac ar- teries was investigated. Quantitative histomorphometry of the stented iliac segments 28 days after the implantation indicated that palladium-103 stents made a significant reduction in neointimal area and percent area stenosis com- pared with the nonradioactive stents. Lumen area in the palladium-103 stents treatment group was larger than the control group. However, the reduction of neointima formation by palladium-103 stents implantation was in a non-dose-dependent fashion. Low ionizing radiation doses via γ-emitting palladium-103 stent are effective in pre- venting neointimal hyperplasia in iliac arteries of rabbits. Palladium-103 stents can be employed as a possible novel means to prevent in-stent restenosis.
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页码：35 / 39
页数：5
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