Effect of Kangxin decoction on cardiomyocyte apoptosis and PI3K/Akt/FoxO1 signaling pathway in ischemic cardiomyopathy rats model

被引:0
|
作者
郭进建 [1 ]
机构
[1] Dept Cardiol,2nd Affil Hosp,Fujian TCM Univ
关键词
Akt; Effect of Kangxin decoction on cardiomyocyte apoptosis and PI3K/Akt/FoxO1 signaling pathway in ischemic cardiomyopathy rats model; PI;
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暂无
中图分类号
R285.5 [中药实验药理];
学科分类号
摘要
Objective To observe the effect of Kangxin Decoction on the cell apoptosis in a rat model of ischemic cardiomyopathy(ICM),and to explore the underlying mechanisms,including its effects on the expression of PI3K/Akt/Fox O1 signaling pathway.Methods Sixty-six rats were randomly divided into six groups:the sham group,the model group,the Captopril group,the low dose Kangxin Decoction group,the middle dose Kangxin
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页码:196 / 197
页数:2
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