Hepatocellular carcinoma and the risk of occupational exposure

被引:0
|
作者
Venerando Rapisarda [1 ]
Carla Loreto [2 ]
Michele Malaguarnera [3 ]
Annalisa Ardiri [4 ]
Maria Proiti [4 ]
Giuseppe Rigano [4 ]
Evelise Frazzetto [4 ]
Maria Irene Ruggeri [5 ]
Giulia Malaguarnera [6 ]
Nicoletta Bertino [7 ]
Mariano Malaguarnera [6 ]
Vito Emanuele Catania [6 ]
Isidoro Di Carlo [8 ]
Adriana Toro [8 ]
Emanuele Bertino [7 ]
Dario Mangano [1 ]
Gaetano Bertino [4 ]
机构
[1] Occupational Medi-cine Unit, Department of Clinical and Experimental Medicine,University of Catania
[2] Department of Biomedical Sciences, Human Anatomy and Histology Section, University of Catania
[3] Department of Biomedical Sciences,University of Catania
[4] Hepatology Unit, Department of Clinical and Experimental Medicine, University of Catania
[5] Internal Medicine Unit ARNAS Civic Hospital  6. Research Centre “La Grande Senescenza”, University of Catania  7. Faculty of Pharmacy, Universit
关键词
Hepatocellular carcinoma; Autophagy; Epigenetic events; Hepatitis B virus; Hepatitis C virus; Occupational exposure; Chemical agents; Mitophagy; Arsenic; Cadmium;
D O I
暂无
中图分类号
R735.7 [肝肿瘤];
学科分类号
100214 ;
摘要
Hepatocellular carcinoma(HCC)is the most common type of liver cancer.The main risk factors for HCC are alcoholism,hepatitis B virus,hepatitis C virus,nonalcoholic steatohepatitis,obesity,type 2 diabetes,cirrhosis,aflatoxin,hemochromatosis,Wilson’s disease and hemophilia.Occupational exposure to chemicals is another risk factor for HCC.Often the relationship between occupational risk and HCC is unclear and the reports are fragmented and inconsistent.This review aims to summarize the current knowledge regarding the association of infective and non-infective occupational risk exposure and HCC in order to encourage further research and draw attention to this global occupational public health problem.
引用
收藏
页码:573 / 590
页数:18
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