Interaction Between Variations in Dopamine D2 and Serotonin 2A Receptor is Associated with Short-Term Response to Antipsychotics in Schizophrenia

被引:1
|
作者
Liansheng Zhao [1 ,2 ]
Huijuan Wang [3 ]
Yamin Zhang [1 ,2 ]
Jinxue Wei [1 ,2 ]
Peiyan Ni [1 ,2 ]
Hongyan Ren [1 ,2 ]
Gang Li [4 ]
Qiang Wang [1 ,2 ]
Gavin P Reynolds [5 ]
Weihua Yue [6 ,7 ]
Wei Deng [1 ,2 ]
Hao Yan [6 ,7 ]
Liwen Tan [8 ]
Qi Chen [9 ]
Guigang Yang [10 ]
Tianlan Lu [6 ,7 ]
Lifang Wang [6 ,7 ]
Fuquan Zhang [11 ]
Jianli Yang [12 ,13 ]
Keqing Li [14 ]
Luxian Lv [15 ]
Qingrong Tan [16 ]
Yinfei Li [1 ,2 ]
Hua Yu [1 ,2 ]
Hongyan Zhang [6 ,7 ]
Xin Ma [9 ]
Fude Yang [10 ]
Lingjiang Li [8 ]
Chuanyue Wang [9 ]
Huiyao Wang [1 ,2 ]
Xiaojing Li [1 ,2 ]
Wanjun Guo [1 ,2 ]
Xun Hu [17 ]
Yang Tian [1 ,2 ]
Xiaohong Ma [1 ,2 ]
Jeremy Coid [1 ,2 ]
Dai Zhang [6 ,7 ]
Chao Chen [3 ]
Tao Li [1 ,2 ]
机构
[1] Beijing Hui Long Guan Hospital
[2] Wuxi Mental Health Center, Nanjing Medical University
[3] Institute of Mental Health, Tianjin Anding Hospital
[4] Tianjin Medical University General Hospital, Tianjin Medical University
[5] Hebei Mental Health Center
[6] Second Affiliated Hospital of Xinxiang Medical University
[7] Department of Psychiatry, Xijing Hospital, Fourth Military Medical University
[8] Huaxi Biobank, West China Hospital of Sichuan University
[9] Psychiatric Laboratory and Mental Health Center, the State Key Laboratory of Biotherapy, West China Hospital of Sichuan University
[10] West China Brain Research Center, West China Hospital of Sichuan University
[11] The National Engineering Research Center for Miniaturized Detection Systems, College of Life Science, Northwest University
[12] Shaanxi Lifegen Co., Ltd
[13] Biomolecular Science Research Centre, Sheffield Hallam University
[14] Peking University Sixth Hospital(Institute of Mental Health)
[15] National Clinical Research Center for Mental Disorders and Key Laboratory of Mental Health, Ministry of Health(Peking University)
[16] Second Xiangya Hospital, Central South University
[17] Beijing Anding Hospital, Beijing Institute for Brain Disorders, Capital Medical University
基金
中国国家自然科学基金;
关键词
Interaction Between Variations in Dopamine D2 and Serotonin 2A Receptor is Associated with Short-Term Response to Antipsychotics in Schizophrenia;
D O I
暂无
中图分类号
R749.3 [精神分裂症];
学科分类号
摘要
Dear Editor,Schizophrenia is a chronic and debilitating brain disorder,which has a strong genetic component with heritability ranging from 66%to 85%[1, 2]. Currently, antipsychotic drugs remain the most effective treatment for the psychotic
引用
收藏
页码:1102 / 1105
页数:4
相关论文
共 50 条
  • [41] Lack of association between two dopamine D2 receptor gene polymorphisms and schizophrenia
    Caprini, Sara
    Saetre, Peter
    Melle, Ingrid
    Djurovic, Srdjan
    Andreassen, Ole A.
    Skjodt, Celina
    Duong, Linh
    Werge, Thomas
    Hall, Hakan
    Agartz, Ingrid
    Terenius, Lars
    Jonsson, Erik G.
    PSYCHIATRIC GENETICS, 2011, 21 (04) : 214 - 215
  • [42] The dopamine receptor D2 genotype is associated with hyperprolactinemia
    Hansen, KA
    Zhang, YY
    Colver, R
    Tho, SPT
    Plouffe, L
    McDonough, PG
    FERTILITY AND STERILITY, 2005, 84 (03) : 711 - 718
  • [43] Interaction of the dopamine D2 receptor and endogenous β-arrestin 1 and 2
    Macey, TA
    Neve, KA
    FASEB JOURNAL, 2003, 17 (04): : A638 - A638
  • [45] Preferential interaction between the dopamine D2 receptor and arrestin2 in neostriatal neurons
    Macey, TA
    Gurevich, VV
    Neve, KA
    MOLECULAR PHARMACOLOGY, 2004, 66 (06) : 1635 - 1642
  • [46] Comparative pharmacology of antipsychotics possessing combined dopamine D2 and serotonin 5-HT1A receptor properties
    Adrian Newman-Tancredi
    Mark S. Kleven
    Psychopharmacology, 2011, 216 : 451 - 473
  • [47] Interaction between serotonin transporter and dopamine D2/D3 receptor radioligand measures is associated with harm avoidant symptoms in anorexia and bulimia nervosa
    Bailer, Ursula F.
    Frank, Guido K.
    Price, Julie C.
    Meltzer, Carolyn C.
    Becker, Carl
    Mathis, Chester A.
    Wagner, Angela
    Barbarich-Marsteller, Nicole C.
    Bloss, Cinnamon S.
    Putnam, Karen
    Schork, Nicholas J.
    Gamst, Anthony
    Kaye, Walter H.
    PSYCHIATRY RESEARCH-NEUROIMAGING, 2013, 211 (02) : 160 - 168
  • [48] Dopamine D2 receptor antagonism of antipsychotics and the risk of death due to choking
    Luykx, Jurjen J.
    Tanskanen, Antti
    Lahteenvuo, Markku
    Manu, Peter
    Correll, Christoph U.
    Hasan, Alkomiet
    Lieslehto, Johannes
    Taipale, Heidi
    Tiihonen, Jari
    PSYCHIATRY RESEARCH, 2024, 339
  • [49] Dopamine D2, serotonin 2A, and 2C receptor polymorphisms in afrocaribbean inpatients: Differences in association with parkinsonism, tremor, and rigidity
    Al Hadithy, A. F. Y.
    Wilffert, B.
    Stewart, R. E.
    Looman, N. M. G.
    Bruggeman, R.
    Brouwers, J. R. B. J.
    Matrons, G. E.
    van Os, J.
    Hoek, H. W.
    van Harten, P. N.
    NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 2007, 375 : 104 - 104
  • [50] Comparative pharmacology of antipsychotics possessing combined dopamine D2 and serotonin 5-HT1A receptor properties
    Newman-Tancredi, Adrian
    Kleven, Mark S.
    PSYCHOPHARMACOLOGY, 2011, 216 (04) : 451 - 473