STUDIES ON THE STRUCTURE-FUNCTION RELATIONSHIPS OF INSULIN Ⅰ. THE RELATIONSHIP OF THE C-TERMINAL PEPTIDE SEQUENCE OF B-CHAIN TO THE ACTIVITY OF INSULIN

被引：0
|
作者：
The Shanghai Insulin Research Group [1 ]
机构：
[1] 上海胰岛素研究小组
来源：
Science China Mathematics | 1973年 / 01期
关键词：
STUDIES ON THE STRUCTURE-FUNCTION RELATIONSHIPS OF INSULIN; THE RELATIONSHIP OF THE C-TERMINAL PEPTIDE SEQUENCE OF B-CHAIN TO THE ACTIVITY OF INSULIN;
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摘要：
Desoctapeptide insulin, obtained as a product from the tryptie digestion of natural insulin, has been condensed with the synthetic C-terminal octapcptide to regenerate insulin.Deshexapeptide insulin was obtained when glyeylphenylalanine was condensed with desoctapeptide insulin. It was found to possess insulin activtiy, indicating that Bglycine and Bphenylalanine are both essential to biological activity.
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页码：61 / 70
页数：10
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