Association between circulating oxidized low-density lipoprotein and atherosclerotic cardiovascular disease

被引：1
|
作者：
Shen Gao [1 ]
Jing Liu [1 ]
机构：
[1] Department of Epidemiology, Beijing An Zhen Hospital, Capital Medical University,Beijing Institute of Heart,Lung and Blood Vessel Diseases
来源：
慢性疾病与转化医学(英文) | 2017年 / 3卷 / 02期
基金：
中国国家自然科学基金;
关键词：
Oxidized low density lipoprotein; Atherosclerosis; Cardiovascular disease; Subclinical atherosclerosis; Review;
D O I：
暂无
中图分类号：
O [数理科学和化学];
学科分类号：
07 ;
摘要：
Atherosclerosis is a chronic, progressive disease which eventually leads to coronary heart disease(CHD), ischemic stroke and other atherosclerotic cardiovascular disease(ASCVD). Numerous studies have demonstrated an atherogenic role of oxidized lowdensity lipoprotein(ox-LDL) in the progression of ASCVD. This article briefly reviews the atherogenic mechanism of ox-LDL, the methods of measuring ox-LDL in the circulation, effect of medical therapy and life-style modification on ox-LDL level, and the association between circulating ox-LDL and atherosclerosis, including clinical ASCVD events and subclinical atherosclerosis, in observational studies.
引用
收藏
页码：89 / 94
页数：6
相关论文
共 50 条
  • [21] Role of oxidized low-density lipoprotein in renal disease
    Heeringa, P
    Tervaert, JWC
    [J]. CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION, 2002, 11 (03): : 287 - 293
  • [22] Femoral atherosclerotic plaques confound the association of circulating oxidized low-density lipoprotein with carotid atherosclerosis. Results from the Asklepios Study
    Rietzschel, E. R.
    Langlois, M. L.
    De Buyzere, M. L.
    De Bacquer, D.
    Bekaert, S.
    Blaton, V.
    De Backer, G. G.
    Gillebert, T. C.
    [J]. EUROPEAN HEART JOURNAL, 2008, 29 : 83 - 83
  • [23] Low-Density Lipoprotein Cholesterol-Lowering Therapy for Atherosclerotic Cardiovascular Disease in the Future
    Abe, Shichiro
    Nishino, Setus
    Kanaya, Tomoaki
    Sakuma, Masashi
    Toyoda, Shigeru
    [J]. AMERICAN JOURNAL OF CARDIOLOGY, 2024, 215
  • [24] Role of macrophage and smooth muscle cell apoptosis in association with oxidized low-density lipoprotein in the atherosclerotic development
    Akishima, Y
    Akasaka, Y
    Ishikawa, Y
    Lijun, Z
    Kiguchi, H
    Ito, K
    Itabe, H
    Ishii, T
    [J]. MODERN PATHOLOGY, 2005, 18 (03) : 365 - 373
  • [25] Circulating levels of oxidized low-density lipoprotein in overt and mild hypothyroidism
    Duntas, LH
    Mantzou, E
    Koutras, DA
    [J]. THYROID, 2002, 12 (11) : 1003 - 1007
  • [26] Effects of statins on circulating oxidized low-density lipoprotein in patients with hypercholesterolemia
    Inami, SE
    Okamatsu, K
    Takano, M
    Takagi, G
    Sakai, S
    Sano, J
    Mizuno, K
    [J]. JAPANESE HEART JOURNAL, 2004, 45 (06): : 969 - 975
  • [27] Alcohol consumption is directly associated with circulating oxidized low-density lipoprotein
    Schroder, H
    Marrugat, J
    Fíto, M
    Weinbrenner, T
    Covas, MI
    [J]. FREE RADICAL BIOLOGY AND MEDICINE, 2006, 40 (08) : 1474 - 1481
  • [28] Tea catechin consumption reduces circulating oxidized low-density lipoprotein
    Inami, Shigenobu
    Takano, Masamichi
    Yamamoto, Masanori
    Murakami, Daisuke
    Tajika, Kenichiro
    Yodogawa, Kenji
    Yokoyama, Shinya
    Ohno, Norihiko
    Ohba, Takayoshi
    Sano, Junko
    Ibuki, Chikao
    Seino, Yoshihiko
    Mizuno, Kyoichi
    [J]. INTERNATIONAL HEART JOURNAL, 2007, 48 (06) : 725 - 732
  • [29] Measuring circulating oxidized low-density lipoprotein to evaluate coronary risk
    Tsimikas, S
    Witztum, JL
    [J]. CIRCULATION, 2001, 103 (15) : 1930 - 1932
  • [30] Association between oxidized low-density lipoprotein and salt sensitivity in Dahl S rats
    Otsuka, Y
    Akimoto, H
    Ishii, T
    Yokokoji, K
    Abeta, H
    Okabe, T
    Kushiro, T
    [J]. CIRCULATION, 1998, 98 (17) : 801 - 801
12345