Association between circulating oxidized low-density lipoprotein and atherosclerotic cardiovascular disease

被引：1
|
作者：
Shen Gao [1 ]
Jing Liu [1 ]
机构：
[1] Department of Epidemiology, Beijing An Zhen Hospital, Capital Medical University,Beijing Institute of Heart,Lung and Blood Vessel Diseases
来源：
慢性疾病与转化医学(英文) | 2017年 / 3卷 / 02期
基金：
中国国家自然科学基金;
关键词：
Oxidized low density lipoprotein; Atherosclerosis; Cardiovascular disease; Subclinical atherosclerosis; Review;
D O I：
暂无
中图分类号：
O [数理科学和化学];
学科分类号：
07 ;
摘要：
Atherosclerosis is a chronic, progressive disease which eventually leads to coronary heart disease(CHD), ischemic stroke and other atherosclerotic cardiovascular disease(ASCVD). Numerous studies have demonstrated an atherogenic role of oxidized lowdensity lipoprotein(ox-LDL) in the progression of ASCVD. This article briefly reviews the atherogenic mechanism of ox-LDL, the methods of measuring ox-LDL in the circulation, effect of medical therapy and life-style modification on ox-LDL level, and the association between circulating ox-LDL and atherosclerosis, including clinical ASCVD events and subclinical atherosclerosis, in observational studies.
引用
收藏
页码：89 / 94
页数：6
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