Design,synthesis,in vitro evaluation of tetrahydropyrimidine-isatin hybrids as potential antibacterial,antifungal and anti-tubercular agents

被引：7
|
作者：
Tarunkumar Nanjibhai Akhaja [1 ]
Jignesh Priyakant Raval [1 ]
机构：
[1] Department of Pharmaceutical Chemistry,Ashok & Rita Patel Institute of Integrated Study and Research in Biotechnology and Allied Sciences(ARIBAS),New Vallabh Vidyanagar-388121,Gujarat,India
来源：
ChineseChemicalLetters | 2012年 / 23卷 / 04期
关键词：
Tetrahydropyrimidines; Isatin; 1,3-Dihydro-2H-indol-2-ones; Biginelli reaction; CaCl2; catalyst; In vitro antituberculer activity; Antibacterial and antifungal activity;
D O I：
暂无
中图分类号：
TQ465 [抗菌素制造];
学科分类号：
100705 ;
摘要：
A series of 5-substitued-3-(5-(4-(furan-2-yl)-6-methyl-2-oxo/thioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-1,3,4-thiadiazol-2- ylimino)indolin-2-one derivatives were synthesized,characterized and were screened for anti-bacterial,anti-fungal and antitubercular activity.
引用
收藏
页码：446 / 449
页数：4
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