Expression of prothymosin α predicts early recurrence and poor prognosis of hepatocellular carcinoma

被引：0
|
作者：
Sang Yun Ha [1 ]
Dae Hyun Song [1 ]
Soo Hyun Hwang [1 ]
Soo Youn Cho [1 ]
Cheol-Keun Park [1 ]
机构：
[1] Department of Pathology,Samsung Medical Center,Sungkyunkwan University School of Medicine
来源：
Hepatobiliary & Pancreatic Diseases International | 2015年 / 14卷 / 02期
关键词：
prothymosin a; hepatocellular carcinoma; recurrence;
D O I：
暂无
中图分类号：
R735.7 [肝肿瘤];
学科分类号：
100214 ;
摘要：
BACKGROUND:Prothymosinα(PTMA)is a nuclear oncoprotein-transcription factor essential for cell cycle progression and proliferation.PTMA was overexpressed in several human malignancies including hepatocellular carcinoma(HCC).However,the prognostic significance of PTMA protein expression in HCC remains unclear.In the present study,we evaluated PTMA protein expression by immunohistochemistry in order to elucidate the prognostic roles of PTMA in HCC patients.
引用
收藏
页码：171 / 177
页数：7
相关论文
共 50 条
  • [21] Cytokeratin 19 expression in hepatocellular carcinoma predicts early postoperative recurrence
    Uenishi, T
    Kubo, S
    Yamamoto, T
    Shuto, T
    Ogawa, M
    Tanaka, H
    Tanaka, S
    Kaneda, K
    Hirohashi, K
    [J]. CANCER SCIENCE, 2003, 94 (10) : 851 - 857
  • [22] High cathepsin A protein expression predicts poor prognosis and tumor recurrence of hepatocellular carcinoma patients after curative hepatectomy
    Luo, Laibang
    Wang, Xuyang
    Wang, Huaxiang
    Yang, Chengkai
    Zhang, Youfu
    Li, Xinchang
    Xu, Zhidan
    [J]. AMERICAN JOURNAL OF CANCER RESEARCH, 2022, 12 (08): : 3843 - 3856
  • [23] ASPM is a novel marker for vascular invasion, early recurrence, and poor prognosis of hepatocellular carcinoma
    Lin, Shih-Yeh
    Pan, Hung-Wei
    Liu, Shu-Hsiang
    Jeng, Yung-Ming
    Hu, Fu-Chang
    Peng, Shian-Yang
    Lai, Po-Lin
    Hsu, Hey-Chi
    [J]. CLINICAL CANCER RESEARCH, 2008, 14 (15) : 4814 - 4820
  • [24] Akt phosphorylation is a risk factor for early disease recurrence and poor prognosis in hepatocellular carcinoma
    Nakanishi, K
    Sakamoto, M
    Yamasaki, S
    Todo, S
    Hirohashi, S
    [J]. CANCER, 2005, 103 (02) : 307 - 312
  • [25] Increased expression of miR-21 predicts poor prognosis in patients with hepatocellular carcinoma
    Huang, Chang-Shan
    Yu, Wei
    Cui, Hong
    Wang, Yun-Jian
    Zhang, Ling
    Han, Feng
    Huang, Tao
    [J]. INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY, 2015, 8 (06): : 7234 - 7238
  • [26] Multilevel regulation of RUVBL2 expression predicts poor prognosis in hepatocellular carcinoma
    Tao Yan
    Fang Liu
    Jiajia Gao
    Haizhen Lu
    Jianqiang Cai
    Xiaohang Zhao
    Yulin Sun
    [J]. Cancer Cell International, 19
  • [27] Canopy Homolog 2 Expression Predicts Poor Prognosis in Hepatocellular Carcinoma with Tumor Hemorrhage
    Wang, Dong
    Wang, Zhi-Ming
    Zhang, Sai
    Wu, Hai-Jun
    Tao, Yi-Ming
    [J]. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY, 2018, 50 (06) : 2017 - 2028
  • [28] High expression of RPL27A predicts poor prognosis in patients with hepatocellular carcinoma
    Xing, Huiwu
    Jiang, Xiangqi
    Yang, Chenyu
    Tan, Bingqian
    Hu, Jiqiang
    Zhang, Mingman
    [J]. WORLD JOURNAL OF SURGICAL ONCOLOGY, 2023, 21 (01)
  • [29] Low expression of LACTB promotes tumor progression and predicts poor prognosis in hepatocellular carcinoma
    Xue, Chen
    He, Yuting
    Zhu, Weiwei
    Chen, Xiaolong
    Yu, Yan
    Hu, Qiuyue
    Chen, Jianan
    Liu, Liwen
    Ren, Fang
    Ren, Zhigang
    Cui, Guangying
    Sun, Ranran
    [J]. AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH, 2018, 10 (12): : 4152 - 4162
  • [30] High expression of RPL27A predicts poor prognosis in patients with hepatocellular carcinoma
    Huiwu Xing
    Xiangqi Jiang
    Chenyu Yang
    Bingqian Tan
    Jiqiang Hu
    Mingman Zhang
    [J]. World Journal of Surgical Oncology, 21
12345