Seroprevalence of HCV and its co-infection with HBV and HIV among liver disease patients of South Tamil Nadu

被引:0
|
作者
Ganesh Kumar Anbazhagan [1 ,2 ]
Sridharan Krishnamoorthy [1 ,3 ]
Thirunalasundari Thiyagarajan [4 ]
机构
[1] Thirunalasundari Thiyagarajan 620024,Tamil Nadu,India
[2] National Facility for Marine Cyanobacteria,Bharathidasan University
[3] Department of Gastroenterology,KAP Viswanatham Government Medical College and Annal Gandhi Memorial Government Hospital
[4] Department of Biotechnology,Bharathidasan University
关键词
Hepatitis C virus; Hepatitis B virus; Human immunodeficiency virus; Co-infection; Liver function test;
D O I
暂无
中图分类号
R512.6 [病毒性肝炎]; R512.91 [获得性免疫缺陷综合征(AIDS艾滋病)];
学科分类号
100401 ;
摘要
AIM:To determine the seroprevalence of hepatitis C virus(HCV) and its co-infection with hepatitis B virus(HBV),hepatitis delta agent(HDV) and human immunodeficiency virus(HIV) among liver disease patients of south Tamil Nadu. METHODS:A total of 1012 samples comprising 512 clinically diagnosed cases of liver disease patients and 500 apparently healthy age and sex matched individuals were screened for Hepatitis C virus(anti HCV and HCV RNA) ,Hepatitis B virus(HBsAg),Hepatitis delta agent(anti HDV) and Human immuno virus(antibodies to HIV-1 and HIV-2) using commercially available enzyme linked immunosorbent assay kits.HCV RNA wasdetected by RT-PCR.Liver function tests like ALT,AST,GGT,ALP,bilirubin and albumin were also studied. RESULTS:The seroprevalence of HCV was found to be 5.6%among liver disease patients by ELISA.27/512,49/512 and 12/512 patients were positive for HIV,HBV &HDV respectively.Co-infection of HCV&HBV was found in 8 patients,with 6 for HCV&HIV and 4 for HCV,HBV&HIV co-infections.Sex-wise analysis showed that HIV,HCV&HBV and HCV&HIV co-infection was high among females whereas for HBV it was high in males. The mean ALT and AST in HCV positive cases were 42.1±8.3 and 49±10.1.In people co-infected with HCV&HBV or HCV&HIV or HCV,HBV&HIV the mean ALT of 58.0±03.16,56.78±4.401 and 64.37±4.01 respectively. CONCLUSION:We strongly recommend routine test of the blood for HCV in addition to HBV and HIV.We also recommend individualized counseling to identify those at risk and testing for those who want it.Improved surveillance and periodic epidemiological studies will have to be undertaken to monitor and prevent these blood-borne viruses.
引用
收藏
页码:42 / 48
页数:7
相关论文
共 50 条
  • [41] HIV/HCV CO-INFECTION AND RISK OF LIVER STEATOSIS:THE ROLE OF TENOFOVIR
    Borghi, V.
    Mussini, C.
    Bisi, L.
    Manzini, L.
    INFECTION, 2009, 37 : 47 - 47
  • [42] Seroprevalence of HBV and HCV among HIV-infected adults in China according to route of HIV infection: high rate of HBV and HCV exposure
    Zhang, Fujie
    Zhou, Shuntai
    Chen, Xi
    Ji, Guoping
    Lu, Ying
    Wu, Yasong
    Liu, Zhongfu
    Shang, Hong
    FUTURE VIROLOGY, 2012, 7 (10) : 1015 - 1020
  • [43] Is physician assessment of alcohol consumption useful in predicting risk of severe liver disease among people with HIV and HIV/HCV co-infection?
    Shanyinde, Milensu
    Girardi, Enrico
    Puoti, Massimo
    De Luca, Andrea
    Sighinolfi, Laura
    Caterina, Uberti Foppa
    Caramello, Pietro
    Lampe, Fiona C.
    Monforte, Antonella D'Arminio
    Cozzi-Lepri, Alessandro
    Monforte, A. D'Arminio
    Andreoni, M.
    Angarano, G.
    Antinori, A.
    Castelii, F.
    Cauda, R.
    Di Perri, G.
    Galli, M.
    Iardino, R.
    Ippoiito, G.
    Lazzarin, A.
    Perno, C. F.
    von Schloesser, F.
    Viale, P.
    Castagna, A.
    Ceccherini-Siiberstein, F.
    Cozzi-Lepri, A.
    Girard, E.
    Lo Caputo, S.
    Mussini, C.
    Puoti, M.
    Andreoni, Committee M.
    Ammassari, A.
    Balotta, C.
    Bandera, A.
    Bonfanti, P.
    Bonora, S.
    Border, M.
    Calcagno, A.
    Calza, L.
    Capobianchi, M. R.
    Ceccherini-Silberstein, F.
    Cingolani, A.
    Cinque, P.
    De Luca, A.
    Di Biagio, A.
    Girardi, E.
    Gianotti, N.
    Gori, A.
    Guaraldi, G.
    BMC PUBLIC HEALTH, 2019, 19 (01)
  • [44] Is physician assessment of alcohol consumption useful in predicting risk of severe liver disease among people with HIV and HIV/HCV co-infection?
    Milensu Shanyinde
    Enrico Girardi
    Massimo Puoti
    Andrea De Luca
    Laura Sighinolfi
    Uberti Foppa Caterina
    Pietro Caramello
    Fiona C. Lampe
    Antonella D’Arminio Monforte
    Alessandro Cozzi-Lepri
    BMC Public Health, 19
  • [45] A Retrospective Seroprevalence Study of Dengue, Chikungunya and Co-Infection virus: A Hospital Based Study from Theni, Tamil Nadu
    Gopinath, R.
    Dhanasezhiyan, A.
    Krishnapriya, S.
    Prasanth, S. Mathan
    Thangam, G. Sucila
    JOURNAL OF PURE AND APPLIED MICROBIOLOGY, 2023, 17 (03): : 1700 - 1707
  • [46] Prevalence of HBV/HCV Co-Infection and Associated Risk Factors in People Living with HIV
    Senoglu, Sevtap
    Yesilbag, Zuhal
    Karaosmanoglu, Hayat Kumbasar
    Aydin, Ozlem Altuntas
    HEPATITIS MONTHLY, 2020, 20 (04)
  • [47] Toxoplasma gondii, HBV, and HCV co-infection and their correlation with CD4 cells among Iranian HIV-positive patients
    Bazmjoo, Ahmadreza
    Bagherzadeh, Mohammad Aref
    Raoofi, Rahim
    Taghipour, Ali
    Mazaherifar, Samaneh
    Sotoodeh, Hojatallah
    Ostadi, Zahra
    Shadmand, Enayat
    Jahromi, Mirza A. M.
    Abdoli, Amir
    IMMUNITY INFLAMMATION AND DISEASE, 2023, 11 (02)
  • [48] HCV and HIV co-infection: Prevalence genotype distribution and severity of liver disease by in an urban HIV clinic.
    Sulkowski, MS
    Brinkley-Laughton, S
    Thomas, DL
    HEPATOLOGY, 2000, 32 (04) : 212A - 212A
  • [49] HCV/HIV co-infection: time to re-evaluate the role of HIV in the liver?
    Blackard, J. T.
    Sherman, K. E.
    JOURNAL OF VIRAL HEPATITIS, 2008, 15 (05) : 323 - 330