Synthesis of N1-Substituted-3-aryl-4-alkyl-4, 5-dihydro-1H-1-pyra-zolethiocarboxamide as Novel Small Molecule Inhibitors of Cysteine Protease of T.cruzi

被引:0
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作者
Chun GUO1*
机构
关键词
N1-substituted-3-aryl-4-alkyl-4; 5-dihydro-1H-1-pyrazolethiocarboxamide; synthesis; T.cruzi. cysteine protease inhibitor;
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暂无
中图分类号
O625 [芳香族化合物];
学科分类号
070303 ; 081704 ;
摘要
A series of N1-substituted-3-aryl-4-alkyl-4, 5-dihydro-1H-1-pyrazolethiocarboxamide were prepared from the Mannich bases of aryl ketones in good yields. Some derivatives were found to be active against the cysteine protease of T.cruzi..
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页码:1043 / 1046
页数:4
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