Synthesis of N1-Substituted-3-aryl-4-alkyl-4, 5-dihydro-1H-1-pyra-zolethiocarboxamide as Novel Small Molecule Inhibitors of Cysteine Protease of T.cruzi

被引：0
|
作者：
Chun GUO1*
机构：
来源：
Chinese Chemical Letters | 2002年 / 11期
关键词：
N1-substituted-3-aryl-4-alkyl-4; 5-dihydro-1H-1-pyrazolethiocarboxamide; synthesis; T.cruzi. cysteine protease inhibitor;
D O I：
暂无
中图分类号：
O625 [芳香族化合物];
学科分类号：
070303 ; 081704 ;
摘要：
A series of N1-substituted-3-aryl-4-alkyl-4, 5-dihydro-1H-1-pyrazolethiocarboxamide were prepared from the Mannich bases of aryl ketones in good yields. Some derivatives were found to be active against the cysteine protease of T.cruzi..
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页码：1043 / 1046
页数：4
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