Current status and future of targeted peptide receptor radionuclide positron emission tomography imaging and therapy of gastroenteropancreatic-neuroendocrine tumors

被引:0
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作者
Neil Grey [1 ]
Michael Silosky [2 ]
Christopher H Lieu [3 ]
Bennett B Chin [2 ]
机构
[1] Radiology-Nuclear Medicine, University of Colorado School of Medicine, Anschutz Medical Campus
[2] Medical Oncology, University of Colorado School of Medicine, Anschutz Medical Campus
[3] Department of Radiology, University of Colorado School of Medicine, Anschutz Medical Campus
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R735 [消化系肿瘤];
学科分类号
100214 ;
摘要
Theranostics is the highly targeted molecular imaging and therapy of tumors.Targeted peptide receptor radionuclide therapy has taken the lead in demonstrating the safety and effectiveness of this molecular approach to treating cancers.Metastatic, well-differentiated gastroenteropancreatic neuroendocrine tumors may be most effectively imaged and treated with DOTATATE ligands. We review the current practice, safety, advantages, and limitations of DOTATATE based theranostics. Finally, we briefly describe the exciting new areas of development and future directions of gastroenteropancreatic neuroendocrine tumor theranostics.
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页码:1768 / 1780
页数:13
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