Recent advances in the identification of the host factors involved in dengue virus replication

被引：0
|
作者：
Yi Wang [1 ,2 ]
Ping Zhang [1 ,2 ]
机构：
[1] Department of Immunology, Institute of Human Virology, Zhongshan School of Medicine, Sun Yat-sen University
[2] Key Laboratory of Tropical Diseases Control(Sun Yat-sen University), Ministry of Education
来源：
Virologica Sinica | 2017年 / 01期
基金：
中国国家自然科学基金;
关键词：
dengue virus(DENV); host factors; replication; proteins; miRNAs;
D O I：
暂无
中图分类号：
R373 [人体病毒学（致病病毒）];
学科分类号：
100103 ; 100705 ;
摘要：
Dengue virus(DENV) belongs to the genus Flavivirus of the family Flaviviridae and it is primarily transmitted via Aedes aegypti and Aedes albopictus mosquitoes. The life cycle of DENV includes attachment, endocytosis, protein translation, RNA synthesis, assembly, egress, and maturation.Recent researches have indicated that a variety of host factors, including cellular proteins and micro RNAs, positively or negatively regulate the DENV replication process. This review summarizes the latest findings(from 2014 to 2016) in the identification of the host factors involved in the DENV life cycle and Dengue infection.
引用
收藏
页码：23 / 31
页数：9
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