Siderochelins with anti-mycobacterial activity from Amycolatopsis sp. LZ149

被引:0
|
作者
LU Chun-Hua [1 ]
YE Fang-Wen [2 ]
SHEN Yue-Mao [1 ,2 ]
机构
[1] Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Shandong University
[2] School of Life Sciences, Xiamen University
关键词
Amycolatopsis sp.LZ149; Siderochelin; Bioassay-guided; Mycobacterium smegmatis; X-ray single crystal diffraction;
D O I
暂无
中图分类号
R284 [中药化学];
学科分类号
摘要
Three new compounds, namely siderochelins D(2), E(3), and F(4), together with one known siderochelin A(1), were isolated from Amycolatopsis sp. LZ149 and elucidated by spectroscopic analyses including1D- and 2D-NMR and X-ray single crystal diffraction. Compounds 1-3 showed antibacterial activity against Mycobacterium smegmatis.
引用
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页码:69 / 72
页数:4
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