SmI2-Mediated Addition Reaction of α-Halomethylsulfones to Carbonyl Compounds.A Convenient Synthesis of β-Hydroxysulfones

被引：0
|
作者：
黄宪
段德慧
金红卫
机构：
[1] Department of Chemistry
[2] Zhejiang University(Xixi Campus)
[3] Hangzhou
[4] Zhejiang 310028
[5] China
来源：
ChineseJournalofChemistry | 2003年 / 07期
基金：
中国国家自然科学基金;
关键词：
SmI2-mediated addition; synthesis; β-hydroxysul-fones; α-halo-β-hydroxysulfones;
D O I：
暂无
中图分类号：
O621 [有机化学一般性问题];
学科分类号：
070303 ; 081704 ;
摘要：
Due to the chemoselective dehalogenation by SmI, the additionof α-halomethylsulfones to carbonyl compounds afforded β-hy-droxysulfones. Those reactions with α-bromomethylsulfonesgave the products in moderate to good yields. The SmI-mediat-ed addition of gem-dihalomethylsulfones to ketones also afford-ed α-halo-β-hydroxysulfones in moderate yields.
引用
收藏
页码：917 / 920
页数：4
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