Synthesis of Two New Chiral Blocks for the Construction of Peptide Nucleic Acid (PNA)

被引:0
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作者
Li Gang ZHANG
Ji Mei MIN
Li He ZHANG(National Laboratory of Natural and Biomimetic Drugs. Bet-ling Medical Unlversity.Beijing 100083)
机构
关键词
Peptide nucleic acid (PNA); lysine; synthcsis;
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中图分类号
O629.74 [核酸];
学科分类号
070303 ; 081704 ;
摘要
AnewtypeofDNAmimictermedPNA(PeptideNtlcleicAcid).wasfirstpreparedbyNielsenela/’intileearly1990s.ItisanoligonucleotideanalogueinwhichtheentiredeoxyribosephosphatebackbonehasbeenreplacedbyachemicallycompletelydilTerent.butstructurallyhomomorphousachira...
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页码:195 / 198
页数:4
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