Synthesis of two new chiral blocks for the construction of peptide nucleic acid (PNA)

被引：0

作者：

Zhang, LG ^{[1
]}

Min, JM ^{[1
]}

Zhang, LH ^{[1
]}

机构：

[1] Beijing Med Univ, Natl Lab Nat & Biomimet Drugs, Beijing 100083, Peoples R China

来源：

CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE | 1999年 / 20卷 / 08期

关键词：

peptide nucleic acid (PNA); lysine; synthesis;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Protected (L) and (D)-lysine were used respectively as starting materials to synthesize. two new types of chiral blocks for the construction of PNA. Nucleobase was linked to alpha-NH2 of lysine via -CH2C(O)- spacer in type I, and -C(O)- was used in type II.

引用

页码：1224 / 1229

页数：6

共 5 条

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