Ultrasound-assisted synthesis and preliminary bioactivity of novel 2H-1,2,4-thiadiazolo[2,3-a]pyrimidine derivatives containing fluorine

被引：1

作者：

Mao Rong Wang

机构：

来源：

Chinese Chemical Letters | 2012年 / 23卷 / 05期

关键词：

2H-1,2,4-Thiadiazolo[2,3-a]pyrimidine; Synthesis; Ultrasound; Bioactivity;

D O I：

暂无

中图分类号：

O626.41 [间（二）氮苯（嘧啶）族];

学科分类号：

070303 ; 081704 ;

摘要：

Eight novel 5,7-disubstituted-2-{5-methyl-3-(4-trifluoromethylphenyl)isoxazol-4-ylcarbonylimino}-2H-1,2,4-thiadiazolo[2,3- a]pyrimidines were synthesized by multi-step reactions in yields 68-85%.Reactions were carried out either by ultrasound irradiation or conventional method,and found it was faster and more efficient under ultrasonic irradiation.Preliminary herbicidal activities against Echinochloa crus-galli,Digitaria sanguinalis and Chenopodium serotinum were also evaluated by flat-utensil method,and the results indicated that the target compounds exhibited significant activities,some were even higher than the control herbicide.

引用

页码：561 / 564

页数：4

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