Determination of IgA,IgG,IgM Class-Specific Rheumatoid Factor and Its Clinical Evaluation

被引：0
|
作者：
李晓军
武建国
机构：
[1] Second Military Medical University
[2] Nanjing 210002
[3] Shanghai 200433 and Department of Clinical Immunology
[4] the Department of Clinical Immunology of General Hospital of Nanjing Command of PLA Nanjing
来源：
Military Medical Research | 1989年 / 04期
关键词：
rheumatoid factor; ELISA; rheumatoid arthritis;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Solid Phase enzyme-linked Immunosorbent assay(ELISA) for detectingclass-specific rheumatoid factor (RF) was established.Aggregated rabbit lgG was used ascoating antigen and the presence of RF was demonstrated by F(ab’)fragment of anti-humanIg conjugated to horseradish peroxidase(HRP).The results showed that high levels ofIgM-RF,IgG-RF and IgA-RF were found in patients with rheumatoid arthritis.A positive cor-relation existed between IgM-,IgG-,IgA-RF and disease activity.The presence of vasculitis al-so correlated positively with the levels of 3 class-specific RFs.
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页码：361 / 364
页数：4
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