DETECTION OF HUMAN HERPESVIRUS 6(HHV-6) DNA IN SALIVARY GLANDS BY THE POLYMERASE CHAIN REACTION

被引:0
|
作者
赵继志
范宏宇
沐桂藩
沈晓东
程效东
机构
[1] Beijing 100005
[2] Beijing 100730
[3] CAMS & PUMC
[4] CAMS&PUMC
[5] Department of Microbiology and Immunology
[6] Department of Stomatology
[7] Institute of Basic Medical Sciences
[8] Peking Union Medical College Hospital
关键词
human herpesvirus 6; salivary gland; polymerase chain reaction;
D O I
暂无
中图分类号
R446.5 [微生物学检验];
学科分类号
摘要
To assess the presence of HHV-6-Specific DNA in human salivary glands, eighteen specimens of salivary gland tissue were investigated using the polymerase chain reaction. Eight of nine parotid glands, five of seven submandibular glands and one of two sublingual glands were found to have amplification of the HHV-6-specific sequence. The findings suggest that salivary gland tissue is one of the potential sites for HHV-6 persistence following primary infection and that saliva is a vehicle for transmission of the virus.
引用
收藏
页码:126 / 128
页数:3
相关论文
共 50 条
  • [1] DETECTION OF HHV-6 BY THE POLYMERASE CHAIN-REACTION
    COLLANDRE, H
    AUBIN, JT
    AGUT, H
    BECHET, JM
    MONTAGNIER, L
    JOURNAL OF VIROLOGICAL METHODS, 1991, 31 (2-3) : 171 - 180
  • [2] Human herpesvirus 6 (HHV-6)
    Lusso, P
    ANTIVIRAL RESEARCH, 1996, 31 (1-2) : 1 - 21
  • [3] Meningoencephalitis caused by Human Herpesvirus 6 (HHV-6)
    Melo, Ana
    Celestino, Catarina
    Silva, Pedro
    Pereira, Eduarda
    Cerejo, Antonio
    Dias, Celeste
    EUROPEAN JOURNAL OF ANAESTHESIOLOGY, 2010, 27 : S13 - S13
  • [4] Quantitation of human herpesvirus-6 (HHV-6) DNA in a cord blood transplant recipient with chromosomal integration of HHV-6
    Kobayashi, D.
    Kogawa, K.
    Imai, K.
    Tanaka, T.
    Hiroi, S.
    Satoh, H.
    Tanaka-Taya, K.
    Nonoyama, S.
    TRANSPLANT INFECTIOUS DISEASE, 2011, 13 (06) : 650 - 653
  • [5] PATHOGENESIS OF HUMAN HERPESVIRUS-6 (HHV-6)
    YAMANISHI, K
    INFECTIOUS AGENTS AND DISEASE-REVIEWS ISSUES AND COMMENTARY, 1992, 1 (03): : 149 - 155
  • [6] Comparison of the Levels of Human Herpesvirus 6 (HHV-6) DNA and Cytokines in the Cerebrospinal Fluid and Serum of Children With HHV-6 Encephalopathy
    Kawabe, Shinji
    Ito, Yoshinori
    Ohta, Rieko
    Sofue, Ayako
    Gotoh, Kensei
    Morishima, Tsuneo
    Kimura, Hiroshi
    JOURNAL OF MEDICAL VIROLOGY, 2010, 82 (08) : 1410 - 1415
  • [7] Specific detection and quantification of human herpesvirus 6 (HHV-6) variants A and B
    Agut, H.
    Boutolleau, D.
    Gautheret-Dejean, A.
    JOURNAL OF CLINICAL VIROLOGY, 2006, 37 : S101 - S101
  • [8] HUMAN HERPESVIRUS 6 (HHV-6) MENINGITIS IN AN ADULT PATIENT
    Maniam, G. B.
    Wilkerson, H.
    Milton, S.
    JOURNAL OF INVESTIGATIVE MEDICINE, 2020, 68 (02) : 439 - 439
  • [9] Characterization of the catalytic subunit of the human herpesvirus 6 (HHV-6) DNA polymerase expressed in an in vitro transcription/translation assay
    De Bolle, L
    Balzarini, J
    De Clercq, E
    Naesens, L
    NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS, 2003, 22 (5-8): : 999 - 1001
  • [10] Human herpesvirus 6 (HHV-6) disease in the setting of transplantation
    Zerr, Danielle M.
    CURRENT OPINION IN INFECTIOUS DISEASES, 2012, 25 (04) : 438 - 444