MAPK signal pathways in the regulation of cell proliferation in mammalian cells

被引：6
|
作者：
WEI ZHANG
机构：
来源：
Cell Research | 2002年 / 01期
关键词：
MAPK; ER.K; JNK/SPAK; p38; cell proliferation; cross-talk;
D O I：
暂无
中图分类号：
Q952 [动物细胞学];
学科分类号：
071009 ;
摘要：
MAPK families play an important role in complex cellular programs like proliferation, differentiation, development, transformation, and apoptosis. At least three MAPI(families have been characterized: extracellular signal-regulated kinase (ERK), Jun kinase (JNK/SAPK) and p38 MAPK. The above effects are fulfilled by regulation of cell cycle engine and other cell proliferation related proteins. In this paper we discussed their functions and cooperation with other signal pathways in regulation of cell proliferation.
引用
收藏
页码：9 / 18
页数：10
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