Effects of β-TCP Ceramics on Osteoblast Cellular Proliferating,Mineralization and Osteocalcin Expression

被引：0

作者：

齐志涛

张启焕

机构：

[1] School of Chemical and Biological Engineering, Yancheng Institute of Technology

[2] The Bio-material Research and Engineering Center, Wuhan University of Technology

来源：

Journal of Wuhan University of Technology(Materials Science Edition) | 2012年 / 27卷 / 01期

关键词：

β-TCP ceramics; osteoblast; cellular proliferating; mineralization; osteocalcin;

D O I：

暂无

中图分类号：

R687.3 [骨骼手术]; R318.1 [人工脏器与器官];

学科分类号：

080502 ; 1002 ; 100210 ;

摘要：

After co-cultrured osteoblast with β-TCP ceramics, the cellular proliferating, mineralization and osteocalcin expression were studied. MTT assay showed that β-TCP ceramics had no affect on cellular proliferating. Laser scanning confocal detection showed that β-TCP ceramics could increase the mineralization level of osteoblast. Furthermore, RT-PCR showed that β-TCP could increase the expression level of osteocalcin. Those results indicate β-TCP ceramics had perfect biocompatibility and increased the mineralization of osteoblast to accelerate osteogenesis by means of affecting the expression of genes involving in osteogeneticprocess.

引用

页码：107 / 109

页数：3

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