Effects of β-TCP Ceramics on Osteoblast Cellular Proliferating,Mineralization and Osteocalcin Expression

被引：0
|
作者：
齐志涛
张启焕
机构：
[1] School of Chemical and Biological Engineering, Yancheng Institute of Technology
[2] The Bio-material Research and Engineering Center, Wuhan University of Technology
来源：
Journal of Wuhan University of Technology(Materials Science Edition) | 2012年 / 27卷 / 01期
关键词：
β-TCP ceramics; osteoblast; cellular proliferating; mineralization; osteocalcin;
D O I：
暂无
中图分类号：
R687.3 [骨骼手术]; R318.1 [人工脏器与器官];
学科分类号：
080502 ; 1002 ; 100210 ;
摘要：
After co-cultrured osteoblast with β-TCP ceramics, the cellular proliferating, mineralization and osteocalcin expression were studied. MTT assay showed that β-TCP ceramics had no affect on cellular proliferating. Laser scanning confocal detection showed that β-TCP ceramics could increase the mineralization level of osteoblast. Furthermore, RT-PCR showed that β-TCP could increase the expression level of osteocalcin. Those results indicate β-TCP ceramics had perfect biocompatibility and increased the mineralization of osteoblast to accelerate osteogenesis by means of affecting the expression of genes involving in osteogeneticprocess.
引用
收藏
页码：107 / 109
页数：3
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