非编码RNA在脑缺血再灌注损伤中的作用

被引：12
|
作者：
张毅
冯康倪
陈鉴涛
梁孟亚
机构：
[1] 中山大学附属第一医院心脏外科
来源：
中国病理生理杂志 | 2021年 / 37卷 / 02期
基金：
广东省自然科学基金;
关键词：
脑缺血再灌注损伤; 长链非编码RNA; 微小RNA; 细胞凋亡; 自噬;
D O I：
暂无
中图分类号：
R743.3 [急性脑血管疾病（中风）];
学科分类号：
摘要：
<正>脑卒中(stroke)是导致成年人残疾和死亡的第二大病因,缺血性脑卒中约占所有脑卒中病例的87%[1],成为了现代社会健康和生活质量的主要威胁。缺血性脑卒中(ischemic stroke)由于脑血流量严重减少,脑组织缺乏血液和氧气供应,最终导致神经元细胞死亡和脑梗死[2]。目前临床上常用的治疗缺血性脑卒中的方法是及时恢复大脑的血液供应,然而部分病人恢复大脑血供后不仅不能减轻脑缺血引发的神经功能障碍,反而加重脑缺血症状,
引用
收藏
页码：347 / 355
页数：9
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