Expression of Cyclooxygenase-2 in Ovarian Cancer Cell Lines

被引：0
|
作者：
李晓艳
董卫红
王泽华
机构：
[1] Department of Obstetrics and Gynecology Union Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan 430022 China
[2] Department of Obstetrics and Gynecology Union Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan 430022 China
来源：
Current Medical Science | 2005年 / 05期
关键词：
ovarian cancer; cell lines; cyclooxygenase-2;
D O I：
暂无
中图分类号：
R737.31 [卵巢肿瘤];
学科分类号：
100214 ;
摘要：
To investigate the expression of cyclooxygenase-2 (COX-2) in ovarian cancer cell lines, RT-PCR and immunocytochemistry were used to detect the expression of COX-2 in 5 ovarian cancer cell lines. The expression of COX-2 mRNA and protein was detected in all 5 cell lines. It is suggested that COX-2 is expressed in ovarian cancer cell lines, which provides a basis for the chemoprevention of ovarian cancer.
引用
收藏
页码：536 / 537
页数：2
相关论文
共 50 条
  • [31] Expression of cyclooxygenase-2 in renal cell carcinomas
    Hashimoto, H
    Kitahara, KY
    Tokumitsu, M
    Saga, Y
    Kanaeko, S
    Yachiku, S
    [J]. JOURNAL OF UROLOGY, 2003, 169 (04): : 207 - 207
  • [32] CYCLOOXYGENASE-2 EXPRESSION PATTERN IS NOT DIFFERENT IN TYPE I AND TYPE II OVARIAN CANCER
    Zaborowski, M.
    Magnowska, M.
    Surowiak, P.
    Zabel, M.
    Spaczynski, M.
    Nowak-Markwitz, E.
    [J]. INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER, 2013, 23 (08)
  • [33] Cyclooxygenase-2 expression in normal ovaries and epithelial ovarian neoplasms
    Matsumoto, Y
    Ishiko, O
    Deguchi, M
    Nakagawa, E
    Ogita, S
    [J]. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2001, 8 (01) : 31 - 36
  • [34] Cyclooxygenase-2 expression is higher in ovarian cancer tissue adjacent to endometriosis than in ovarian cancer without comorbid endometriosis
    Chou, YC
    Chen, YJ
    Lai, CR
    Wang, PH
    Hsin-Chan
    Yuan, CC
    [J]. EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY, 2006, 124 (01) : 101 - 105
  • [35] The influence of cyclooxygenase-1 expression on the efficacy of cyclooxygenase-2 inhibition in head and neck squamous cell carcinoma cell lines
    Park, Seok-Woo
    Kim, Hyo-Sun
    Choi, Myung-Sun
    Kim, Ji-Eun
    Jeong, Woo-Jin
    Heo, Dae-Seog
    Sung, Myung-Whun
    [J]. ANTI-CANCER DRUGS, 2011, 22 (05) : 416 - 423
  • [36] Effects of selective cyclooxygenase-2 inhibitors etoricoxib and celecoxib on colorectal cancer cell lines
    Rotelli, M. T.
    Rinaldi, M.
    Gelao, L.
    Bocale, D.
    Portincasa, P.
    Altomare, D. F.
    [J]. EUROPEAN JOURNAL OF CLINICAL INVESTIGATION, 2008, 38 : 42 - 42
  • [37] Expression of cyclooxygenase-1 and cyclooxygenase-2 in human breast cancer
    Hwang, D
    Scollard, D
    Byrne, J
    Levine, E
    [J]. JOURNAL OF THE NATIONAL CANCER INSTITUTE, 1998, 90 (06) : 455 - 460
  • [38] Selenomethionine inhibits growth and suppresses cyclooxygenase-2 (COX-2) protein expression in human colon cancer cell lines
    Baines, A
    Taylor-Parker, M
    Goulet, AC
    Renaud, C
    Gerner, EW
    Nelson, MA
    [J]. CANCER BIOLOGY & THERAPY, 2002, 1 (04) : 370 - 374
  • [39] Requirement of cyclooxygenase-2 expression and prostaglandins for human prostate cancer cell invasion
    Kasem Nithipatikom
    Marilyn A. Isbell
    Paul F. Lindholm
    Andre Kajdacsy-Balla
    Sushma Kaul
    William B. Campell
    [J]. Clinical & Experimental Metastasis, 2002, 19 : 593 - 601
  • [40] Requirement of cyclooxygenase-2 expression and prostaglandins for human prostate cancer cell invasion
    Nithipatikom, K
    Isbell, MA
    Lindholm, PF
    Kajdacsy-Balla, A
    Kaul, S
    Campell, WB
    [J]. CLINICAL & EXPERIMENTAL METASTASIS, 2002, 19 (07) : 593 - 601
12345