Premalignant lesions and gastric cancer: Current understanding

被引:4
|
作者
Athanasios Koulis [1 ,2 ]
ANDrew Buckle [1 ,2 ]
Alex Boussioutas [1 ,2 ,3 ]
机构
[1] Upper Gastrointestinal Translational Laboratory, Peter Mac Callum Cancer Centre
[2] the Sir Peter Mac Callum Department of Surgical Oncology, the University of Melbourne
[3] Department of Medicine, Royal Melbourne Hospital, University of Melbourne
关键词
Helicobacter pylori; Correa cascade; Atrophic gastritis; Intestinal metaplasia; Point of no return; Dysplasia; Stem cells; Gastric cancer;
D O I
暂无
中图分类号
R735.2 [胃肿瘤];
学科分类号
100214 ;
摘要
Over the last two decades there has been a broad paradigm shift in our understanding of gastric cancer(GC) and its premalignant states from gross histological models to increasingly precise molecular descriptions. In this review we reflect upon the historic approaches to describing premalignant lesions and GC, highlight the current molecular landscape and how this could inform future risk assessment prevention strategies.
引用
收藏
页码:665 / 678
页数:14
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