Research on the Extraction of Flavonoids from Ginseng Root and its Ability in Antioxidant

被引:0
|
作者
Ru ZHANG
Bianling ZHANG
Zhiyong LUO
机构
[1] Molecular Biology Research Center,School of Life Sciences,Central South University
[2] College of Chemistry and Chemical Engineering,Hunan Institute of Engineering
基金
中国国家自然科学基金;
关键词
Ginseng root flavonoids; Extraction; Antioxidant; Rat; Activity of SOD;
D O I
暂无
中图分类号
R285 [中药药理学];
学科分类号
1008 ;
摘要
[Objective]The flavonoids were extracted from ginseng root and its antioxidant activity was studied.[Method]The method of ethanol reflow and polyamide enrichment were adopted in the extract of the flavonoids from ginseng root.The antioxidant of the flavonoids from ginseng root was tested with DPPH method,Fenton method and rats feeding.[Results]When the concentration of the ginseng root flavonoids was over 0.5 mg/mL,the scavenging rate of the DPPH free radical was more than 80%and 0.6 mg/mL,the hydroxyl free radical,as high as70.8%.The activity of SOD in rat brain could increase over 17.97%after the rat was fed with the flavonoids at the concentration of 80-120mg/kg per day for five weeks.[Conclusion]The ginseng root flavonoids had a strong scavenging effect on DPPH free radical and hydroxyl free radical in vitro and also an intensifying effect on the activity of SOD in SD rat brain in vivo.
引用
收藏
页码:34 / 37
页数:4
相关论文
共 50 条
  • [31] Optimal extraction and antioxidant activities of flavonoids from Penthorum chinense Pursh
    Fu, Liang
    Yuan, Jingya
    Huang, Juan
    Wang, Handong
    Wang, Qiang
    Xie, Zhou
    Li, Yong
    Wang, Tao
    Feng, Shiling
    Ding, Chunbang
    JOURNAL OF FOOD MEASUREMENT AND CHARACTERIZATION, 2019, 13 (03) : 2253 - 2264
  • [32] Total flavonoids from Hypericum benthamii: Extraction, antioxidant and hypoglycemic activity
    Wang J.
    Lin Y.
    Chen F.
    Shi W.
    Chen Y.
    Jingxi Huagong/Fine Chemicals, 2024, 41 (05): : 1050 - 1059and1083
  • [33] Optimal extraction and antioxidant activities of flavonoids from Penthorum chinense Pursh
    Liang Fu
    Jingya Yuan
    Juan Huang
    Handong Wang
    Qiang Wang
    Zhou Xie
    Yong Li
    Tao Wang
    Shiling Feng
    Chunbang Ding
    Journal of Food Measurement and Characterization, 2019, 13 : 2253 - 2264
  • [34] Extraction of Ginsenosides from American Ginseng (Panax quinquefolium L.) Root
    Dai, Jianming
    Orsat, Valerie
    INTERNATIONAL JOURNAL OF FOOD ENGINEERING, 2010, 6 (03):
  • [35] Ultrasound-cellulase synergy for the extraction of total flavonoids from Astragali complanati Semen and its antioxidant properties
    Zheng, Fangyuan
    Yan, Jie
    Zhu, Miyi
    Ye, Chunlin
    JOURNAL OF APPLIED RESEARCH ON MEDICINAL AND AROMATIC PLANTS, 2024, 43
  • [36] Extraction and antioxidant activity of flavonoids of Morus nigra
    Feng, Rui-Zhang
    Wang, Qin
    Tong, Wen-Zhi
    Xiong, Juan
    Wei, Qin
    Zhou, Wan-Hai
    Yin, Zhong-Qiong
    Yin, Xiao-Ya
    Wang, Li-Ying
    Chen, Ya-Qin
    Lai, Yong-Hong
    Huang, Hong-Yan
    Luo, Qiao-Li
    Wang, Lu
    Jia, Ren-Yong
    Song, Xu
    Zou, Yuan-Feng
    Li, Li-Xia
    INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE, 2015, 8 (12): : 22328 - 22336
  • [37] Efficient Extraction of Flavonoids from Lotus Leaves by Ultrasonic-Assisted Deep Eutectic Solvent Extraction and Its Evaluation on Antioxidant Activities
    Liu, Liangliang
    Xiao, Aiping
    Zhang, Yi
    Duan, Shengwen
    SEPARATIONS, 2023, 10 (02)
  • [38] TOXICITY AND ANTIOXIDANT ACTIVITY OF FLAVONOIDS FROM Lonchocarpus filipes ROOT BARK.
    Santos, Erica L.
    Costa, Emmanoel V.
    Marques, Francisco A.
    Vaz, Nelissa P.
    Sales Maia, Beatriz Helena L. N.
    Magalhaes, Eva G.
    Tozzi, Ana Maria A.
    QUIMICA NOVA, 2009, 32 (09): : 2255 - 2258
  • [39] Flavonoids from Centaurea glomerata and antioxidant activity of its extract
    El Toumy, S. A.
    Omara, E. A.
    Brouard, I
    Bermejo, J.
    PLANTA MEDICA, 2011, 77 (12) : 1332 - 1332
  • [40] Structural characterization of polysaccharides recovered from extraction residue of ginseng root saponins and its fruit nutrition preservation performance
    Sun, Jing
    Zhong, Xinyu
    Sun, Dandan
    Cao, Xinxin
    Yao, Fan
    Shi, Lingling
    Liu, Yujun
    FRONTIERS IN NUTRITION, 2022, 9