Lung injury after cardiopulmonary bypass: Alternative treatment prospects

被引:0
|
作者
Xue-Mei Zheng [1 ]
Zhuo Yang [2 ]
Guang-Li Yang [3 ]
Yan Huang [4 ]
Jie-Ru Peng [5 ]
Meng-Jun Wu [6 ]
机构
[1] School of Medicine, University of Electronic Science and Technology of China
[2] Department of Pharmacy, Chengdu Women’s and Children’s Central Hospital, School of Medicine, University of Electronic Science and Technology of China
[3] Department of Medical Administration, Chengdu Women’s and Children’s Central Hospital, School of Medicine, University of Electronic Science and Technology of China
[4] National Institute of Drug Clinical Trial, Chengdu Women’s and Children’s Central Hospital, School of Medicine, University of Electronic Science and Technology of China
[5] Department of Medical Records Statistics, Chengdu Women’s and Children’s Central Hospital, School of Medicine, University of Electronic Science and Technology of China
[6] Department of Anesthesiology, The Affiliated Hospital, School of Medicine, Chengdu Women's and Children's Central Hospital, University of Electronic Science and Technology
关键词
D O I
暂无
中图分类号
R563 [肺疾病];
学科分类号
1002 ; 100201 ;
摘要
Although the lung injury caused by cardiopulmonary bypass(CPB) has been extensively investigated, the incidence and mortality of lung injury after CPB remain a prominent clinical problem. The poor outcome has been attributed to multifactorial etiology, including the systemic inflammatory response and ischemia reperfusion(I/R) injury during CPB. Lung injury after CPB is a complex pathophysiological process and has many clinical manifestations of mild to severe disease. Which is associated with prognosis. To alleviate this lung injury, interventions that address the pathogenesis are particularly important. This review summarizes the pathogenesis, mechanism and treatment options of lung injury after CPB, such as lung protection with intralipid.
引用
收藏
页码:753 / 761
页数:9
相关论文
共 50 条
  • [21] Pulmonary artery perfusion with protective solution reduces lung injury after cardiopulmonary bypass
    Liu, YL
    Wang, Q
    Zhu, XD
    Liu, DQ
    Pan, SW
    Ruan, YM
    Li, YL
    ANNALS OF THORACIC SURGERY, 2000, 69 (05): : 1402 - 1407
  • [22] Inflammatory Brain Injury After Cardiopulmonary Bypass: Is It Real?
    Nussmeier, Nancy A.
    Searles, Bruce E.
    ANESTHESIA AND ANALGESIA, 2010, 110 (02): : 288 - 290
  • [23] Effects of inosine on reperfusion injury after cardiopulmonary bypass
    Gábor Veres
    Tamás Radovits
    Leila Seres
    Ferenc Horkay
    Matthias Karck
    Gábor Szabó
    Journal of Cardiothoracic Surgery, 5
  • [24] Acute kidney injury in an infant after cardiopulmonary bypass
    Picca, Stefano
    Ricci, Zaccaria
    Picardo, Sergio
    SEMINARS IN NEPHROLOGY, 2008, 28 (05) : 470 - 476
  • [25] Effects of inosine on reperfusion injury after cardiopulmonary bypass
    Veres, Gabor
    Radovits, Tamas
    Seres, Leila
    Horkay, Ferenc
    Karck, Matthias
    Szabo, Gabor
    JOURNAL OF CARDIOTHORACIC SURGERY, 2010, 5
  • [26] LEUKOCYTE DEPLETION AMELIORATES FREE RADICAL-MEDIATED LUNG INJURY AFTER CARDIOPULMONARY BYPASS
    BANDO, K
    PILLAI, R
    CAMERON, DE
    BRAWN, JD
    WINKELSTEIN, JA
    HUTCHINS, GM
    REITZ, BA
    BAUMGARTNER, WA
    JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 1990, 99 (05): : 873 - 877
  • [27] Pulmonary artery perfusion with HTK solution prevents lung injury in infants after cardiopulmonary bypass
    LI JiananLIU YinglongLIU Jinping and LI Xiaofeng Pediatric Cardiac Surgery Center Department of Cardiopulmonary Bypass Fuwai Hospital Chinese Academy of Medical Science and Peking Union Medical CollegeBeijing China
    中华医学杂志(英文版), 2010, (19) : 2645 - 2650
  • [28] EFFECTS OF HYDROXYETHYL STARCH-DEFEROXAMINE ON LUNG INJURY AND MICROVASCULAR PERMEABILITY AFTER CARDIOPULMONARY BYPASS
    STAMLER, A
    WANG, SY
    AGUIRRE, D
    SELLKE, FW
    JOHNSON, RG
    CIRCULATION, 1995, 92 (08) : 2096 - 2096
  • [29] Pulmonary artery perfusion with HTK solution prevents lung injury in infants after cardiopulmonary bypass
    Li Jian-an
    Liu Ying-long
    Liu Jin-ping
    Li Xiao-feng
    CHINESE MEDICAL JOURNAL, 2010, 123 (19) : 2645 - 2650
  • [30] Inflammatory lung injury after cardiopulmonary bypass is attenuated by adenosine A2A receptor activation
    Lisle, Turner C.
    Gazoni, Leo M.
    Fernandez, Lucas G.
    Sharma, Ashish K.
    Bellizzi, Andrew M.
    Schifflett, Grant D.
    Laubach, Victor E.
    Kron, Irving L.
    JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 2008, 136 (05): : 1280 - 1288