Highly efficient base editing in Staphylococcus aureus using an engineered CRISPR RNA-guided cytidine deaminase

With the support by the National Natural Science Foundation of China,the research team directed by Prof.Ji QuanJiang (季泉江)at the School of Physical Science and Technology of ShanghaiTech University,developed a highly efficient single-base editing technique in Staphylococcus aureus,which was published in Chemical Science (2018,9:3248—3253).